国际放射医学核医学杂志
國際放射醫學覈醫學雜誌
국제방사의학핵의학잡지
International Journal of Radiation Medicine and Nuclear Medicine
2015年
5期
363-366
,共4页
阮健磊%刘春旭%吴丽娜%刘建香
阮健磊%劉春旭%吳麗娜%劉建香
원건뢰%류춘욱%오려나%류건향
氡%外周血淋巴细胞%微核率%微核细胞率
氡%外週血淋巴細胞%微覈率%微覈細胞率
동%외주혈림파세포%미핵솔%미핵세포솔
Radon%Peripheral blood lymphocytes%Micronucleus rate%Micronucleus cell frequency
目的 观察氡温泉周边居民外周血淋巴细胞微核率,为氡温泉对健康是否有影响提供依据.方法 采用简单随机抽样法抽取某地氡温泉周边居民42人;同时简单随机抽取生活习惯相似,但未接触过氡温泉的居民44人.采用胞质分裂阻断微核法检测两组居民外周血淋巴细胞微核.结果 氡温泉组的微核率(u=8.26,P＜0.01)和微核细胞率(x2=47.76,P＜0.01)均值显著高于对照组.氡温泉组微核率和微核细胞率随着年龄的增加而增加,且差异具有统计学意义(x2=44.034、27.739,P＜0.01).氡温泉组女性的微核率(u=7.98,P＜0.01)和微核细胞率(x=37.123,P＜0.01)均高于男性且差异具有统计学意义.控制年龄、性别、吸烟和饮酒等混杂因素后,氡暴露与微核率呈高度正相关(x2=57.68,P＜0.01).结论 高氡温泉能够引起居民外周血淋巴细胞微核率增加.
目的 觀察氡溫泉週邊居民外週血淋巴細胞微覈率,為氡溫泉對健康是否有影響提供依據.方法 採用簡單隨機抽樣法抽取某地氡溫泉週邊居民42人;同時簡單隨機抽取生活習慣相似,但未接觸過氡溫泉的居民44人.採用胞質分裂阻斷微覈法檢測兩組居民外週血淋巴細胞微覈.結果 氡溫泉組的微覈率(u=8.26,P＜0.01)和微覈細胞率(x2=47.76,P＜0.01)均值顯著高于對照組.氡溫泉組微覈率和微覈細胞率隨著年齡的增加而增加,且差異具有統計學意義(x2=44.034、27.739,P＜0.01).氡溫泉組女性的微覈率(u=7.98,P＜0.01)和微覈細胞率(x=37.123,P＜0.01)均高于男性且差異具有統計學意義.控製年齡、性彆、吸煙和飲酒等混雜因素後,氡暴露與微覈率呈高度正相關(x2=57.68,P＜0.01).結論 高氡溫泉能夠引起居民外週血淋巴細胞微覈率增加.
목적 관찰동온천주변거민외주혈림파세포미핵솔,위동온천대건강시부유영향제공의거.방법 채용간단수궤추양법추취모지동온천주변거민42인;동시간단수궤추취생활습관상사,단미접촉과동온천적거민44인.채용포질분렬조단미핵법검측량조거민외주혈림파세포미핵.결과 동온천조적미핵솔(u=8.26,P＜0.01)화미핵세포솔(x2=47.76,P＜0.01)균치현저고우대조조.동온천조미핵솔화미핵세포솔수착년령적증가이증가,차차이구유통계학의의(x2=44.034、27.739,P＜0.01).동온천조녀성적미핵솔(u=7.98,P＜0.01)화미핵세포솔(x=37.123,P＜0.01)균고우남성차차이구유통계학의의.공제년령、성별、흡연화음주등혼잡인소후,동폭로여미핵솔정고도정상관(x2=57.68,P＜0.01).결론 고동온천능구인기거민외주혈림파세포미핵솔증가.
Objective To provide the basis for radon spring if there are any adverse effects that radon spring might have on human health by detecting micronucleus rate in peripheral blood lymphocytes of the residents surrounding with radon hot springs.Methods Two groups were drew at simple random.Radon group had 42 residents surrounding with radon hot springs and control group had 44 residents with same living habit without radon hot springs.Cytokinesis-block micronucleus method was used to measure micronucleus in two groups.Results In radon group the averages of micronucleus rate(u=8.26, P＜0.01) and micronucleus cell frequency(x2=47.76, P＜0.01) were significantly higher than control group.In radon group, the micronucleus rate and micronucleus cell frequency were significantly increased with age (x2=44.034, 27.739, both P＜0.01);and the micronucleus rate(u=7.98, P＜0.01) and micronucleus cell frequency (x2=37.123, P＜0.01) of female were significantly higher than male.The micronucleus rate was associated with radon exposure (x2=57.68, P＜ 0.01) controlling of confounding factors such as age, gender, smoking and drinking alcohol.Conclusions High radon springs could cause the increase of the incidence of micronucleus in peripheral blood lymphocyte.
