中国卫生标准管理
中國衛生標準管理
중국위생표준관리
China Health Standard Management
2015年
27期
171-173
,共3页
孙志强%任洪波%段爱红%申自玮%马英%郭燕
孫誌彊%任洪波%段愛紅%申自瑋%馬英%郭燕
손지강%임홍파%단애홍%신자위%마영%곽연
卵巢癌%VEGF%CDl33%免疫组织化学
卵巢癌%VEGF%CDl33%免疫組織化學
란소암%VEGF%CDl33%면역조직화학
Ovarian cancer%VEGF%CDl33%Immunohistochemistry
目的 运用免疫组化法检测CD133和VEGF蛋白在卵巢癌中的表达,并分析它们与临床病理参数的相关性及生物学意义.方法 采用免疫组化法检测60例上皮性卵巢癌组织中CDl33及VEGF的表达情况.结果 (1)随卵巢癌分化程度降低,CD133及VEGF的阳性表达率增高,三组间比较差异均有统计学意义(P<0.05).(2)Spearman相关性分析显示CD133表达与VEGF的表达呈正相关(r=0.663,P<0.05).结论 CDl33及VEGF的表达与上皮性卵巢癌的恶性程度有相关性,且两因子间呈正相关.
目的 運用免疫組化法檢測CD133和VEGF蛋白在卵巢癌中的錶達,併分析它們與臨床病理參數的相關性及生物學意義.方法 採用免疫組化法檢測60例上皮性卵巢癌組織中CDl33及VEGF的錶達情況.結果 (1)隨卵巢癌分化程度降低,CD133及VEGF的暘性錶達率增高,三組間比較差異均有統計學意義(P<0.05).(2)Spearman相關性分析顯示CD133錶達與VEGF的錶達呈正相關(r=0.663,P<0.05).結論 CDl33及VEGF的錶達與上皮性卵巢癌的噁性程度有相關性,且兩因子間呈正相關.
목적 운용면역조화법검측CD133화VEGF단백재란소암중적표체,병분석타문여림상병리삼수적상관성급생물학의의.방법 채용면역조화법검측60례상피성란소암조직중CDl33급VEGF적표체정황.결과 (1)수란소암분화정도강저,CD133급VEGF적양성표체솔증고,삼조간비교차이균유통계학의의(P<0.05).(2)Spearman상관성분석현시CD133표체여VEGF적표체정정상관(r=0.663,P<0.05).결론 CDl33급VEGF적표체여상피성란소암적악성정도유상관성,차량인자간정정상관.
Objective Using immunohistochemical methods to detect CD133 and VEGF protein expression in ovarian cancer,and analyzing their correlation with the clinical pathological parameters and biological significance.Methods Using immunohistochemical method to detect CDl33 in 60 cases of epithelial ovarian cancer tissue and the expression of VEGF.Results (1)With the decreasing of ovarian cancer differentiation degree, the positive expression rate of CD133 and VEGF was obviously increased, compared between the three groups,the difference was statisticaly significant(P<0.05). (2)The Spearman correlation analysis showed positive correlation between the expression of VEGF and expression of CD133(r=0.663, P<0.05).Conclusion CDl33 and VEGF expression correlated with the malignant degree and epithelial ovarian cancer,and the two factors were positively correlated.
