中国卫生标准管理
中國衛生標準管理
중국위생표준관리
China Health Standard Management
2015年
27期
169-170
,共2页
巨噬细胞移动抑制因子%子宫内膜异位症%子宫内膜
巨噬細胞移動抑製因子%子宮內膜異位癥%子宮內膜
거서세포이동억제인자%자궁내막이위증%자궁내막
Macrophage migration inhibitory factor%Endometrial endometriosis%Endometrium
目的 探讨巨噬细胞移动抑制因子在子宫内膜异位症患者子宫内膜中的表达,并分析其临床意义.方法 收集30例不同分期子宫内膜移位症患者的异位内膜、同期30例典型异位内膜组织患者的在位内膜,以30名自愿刮宫的正常人的正常子宫内膜组织为对照.采用免疫组化的方法检测巨噬细胞移动抑制因子的表达水平.结果 结果显示,异位内膜中巨噬细胞移动抑制因子表达水平高于在位内膜,P<0.05,差异具有统计学意义;在位内膜中巨噬细胞移动抑制因子表达水平高于正常内膜,P<0.05,差异具有统计学意义.结论 子宫内膜异位症患者子宫内膜中巨噬细胞移动抑制因子的表达水平提升,这与子宫内膜异位症的形成与发展有着密切的关联性,因此临床上将巨噬细胞移动抑制因子表达水平的检测作为判断治疗子宫内膜异位症的关键依据.
目的 探討巨噬細胞移動抑製因子在子宮內膜異位癥患者子宮內膜中的錶達,併分析其臨床意義.方法 收集30例不同分期子宮內膜移位癥患者的異位內膜、同期30例典型異位內膜組織患者的在位內膜,以30名自願颳宮的正常人的正常子宮內膜組織為對照.採用免疫組化的方法檢測巨噬細胞移動抑製因子的錶達水平.結果 結果顯示,異位內膜中巨噬細胞移動抑製因子錶達水平高于在位內膜,P<0.05,差異具有統計學意義;在位內膜中巨噬細胞移動抑製因子錶達水平高于正常內膜,P<0.05,差異具有統計學意義.結論 子宮內膜異位癥患者子宮內膜中巨噬細胞移動抑製因子的錶達水平提升,這與子宮內膜異位癥的形成與髮展有著密切的關聯性,因此臨床上將巨噬細胞移動抑製因子錶達水平的檢測作為判斷治療子宮內膜異位癥的關鍵依據.
목적 탐토거서세포이동억제인자재자궁내막이위증환자자궁내막중적표체,병분석기림상의의.방법 수집30례불동분기자궁내막이위증환자적이위내막、동기30례전형이위내막조직환자적재위내막,이30명자원괄궁적정상인적정상자궁내막조직위대조.채용면역조화적방법검측거서세포이동억제인자적표체수평.결과 결과현시,이위내막중거서세포이동억제인자표체수평고우재위내막,P<0.05,차이구유통계학의의;재위내막중거서세포이동억제인자표체수평고우정상내막,P<0.05,차이구유통계학의의.결론 자궁내막이위증환자자궁내막중거서세포이동억제인자적표체수평제승,저여자궁내막이위증적형성여발전유착밀절적관련성,인차림상상장거서세포이동억제인자표체수평적검측작위판단치료자궁내막이위증적관건의거.
Objective To study the expression of macrophage migration inhibitory factor in patients with endometrial endometriosis and analyze its clinical significance.MethodsColection of 30 patients with different stages of ectopic endometrium of endometriosis patients,30 patients with typical of ectopic endometrium tissue were in the same period in ectopic,voluntary and curettage in 30 normal endometrial tissue for comparison. Using immunohistochemical methods to detect the expression of macrophage migration inhibitory factor levels. ResultsThe results showed that macrophage migration inhibitory factor in ectopic endometrium expression level was significantly higher than endometrial in the position,P<0.05,the difference was statisticaly significant. In the position expression of macrophage migration inhibitory factor in the level was significantly higher than that of normal endometrium,P<0.05,the difference was statisticaly significant.Conclusion In patients with endometriosis endometrial,the macrophage migration inhibitory factor expression level improved significantly,with the formation and development of endometriosis have close correlation. Therefore,the expression of macrophage migration inhibitory factor is the key for the treatment of endometriosis.
