CAJ | 학술논문

目的：探讨新生儿豆纹血管病变的相关因素，为减少豆纹血管病变相关神经系统后遗症提供依据。方法：选择广东省妇幼保健院收治的447例新生儿，对其行临床资料搜集、豆纹血管超声检查以及其他相关的检查。采用Logistic 回归分析筛选豆纹血管病变的相关因素，P ＜0．05为差异有统计学意义。结果：单因素Logistic 回归分析发现，先天性巨细胞病毒（HCMV）感染、新生儿窒息、先天性心脏病、妊娠期高血压与豆纹血管病变有关（P ＜0．05）。再对这些因素进行多因素Logistic 回归分析显示，先天性HCMV感染、新生儿窒息、先天性心脏病、妊娠期高血压对豆纹血管病变的发生有重要作用（P ＜0．05）。结论：先天性HCMV感染、新生儿窒息，先天性心脏病、妊娠期高血压是新生儿豆纹血管病变的相关因素。提示临床医生应对存在这些相关因素的新生儿进行豆纹血管的超声筛查，早期干预。
목적：탐토신생인두문혈관병변적상관인소，위감소두문혈관병변상관신경계통후유증제공의거。방법：선택광동성부유보건원수치적447례신생인，대기행림상자료수집、두문혈관초성검사이급기타상관적검사。채용Logistic 회귀분석사선두문혈관병변적상관인소，P ＜0．05위차이유통계학의의。결과：단인소Logistic 회귀분석발현，선천성거세포병독（HCMV）감염、신생인질식、선천성심장병、임신기고혈압여두문혈관병변유관（P ＜0．05）。재대저사인소진행다인소Logistic 회귀분석현시，선천성HCMV감염、신생인질식、선천성심장병、임신기고혈압대두문혈관병변적발생유중요작용（P ＜0．05）。결론：선천성HCMV감염、신생인질식，선천성심장병、임신기고혈압시신생인두문혈관병변적상관인소。제시림상의생응대존재저사상관인소적신생인진행두문혈관적초성사사，조기간예。
Objective To investigate the correlation factors of neonatal lenticulostriate vasculopathy. Method Four hundred and forty-seven newborns from Guangdong Women and Children Hospital were enrolled in this study. Clinical data of the newborns were obtained . Brain ultrasound studies of lenticulostriate artery were performed on the newborns. The logistic regression was performed for screening the correlation factors of neonatal lenticulostriate vasculopathy (P < 0.05). Results Results of the univariate logistic regression reveal the correlation factors tcontributing to LSV include congenital cytomegalovirus infection、neonatal asphyxia、congenital heart disease (CHD),hypertensive disorder in pregnancy (P < 0.05, respectively). Multivariate logistic regression analysis was performed on these factors. The congenital cytomegalovirus infection, neonatal asphyxia, CHD,hypertensive disorder in pregnancy were significantly associated with LSV (P < 0.05). Conclusion The congenital cytomegalovirus infection,neonatal asphyxia,CHD,hypertensive disorder in pregnancy are the correlation factors of neonatal lenticulostriate vasculopathy. LSV could be a predictive marker for the future development of neuropsychiatric disorders. The brain ultrasound studies of lenticulostriate artery is suggested to be performed on all infants with the correlation factors.