CAJ | 학술논문

目的：总结老年乳腺癌患者的临床特点，分析其对所采取治疗模式的影响。方法根据患者所处的年龄阶段（60~69岁和≥70岁）将178例接受治疗的老年乳腺癌患者分为A组（103例）和B组（75例）。分析两组患者所采取的治疗方式、疗效及不良反应等差异。结果 A组进行术后辅助化疗的患者比例明显高于B组，差异有统计学意义（P<0.05）；年龄在60~69岁、雌性激素受体阴性及淋巴结转移阳性是术后采取辅助化疗的影响因素（P<0.05）；A组的总有效率高于B组，但差异无统计学意义（P>0.05）；两组均无严重不良反应发生。结论年龄在60~69岁的乳腺癌患者术后宜采取辅助化疗，≥70岁的乳腺癌患者可采取内分泌辅助治疗。
목적：총결노년유선암환자적림상특점，분석기대소채취치료모식적영향。방법근거환자소처적년령계단（60~69세화≥70세）장178례접수치료적노년유선암환자분위A조（103례）화B조（75례）。분석량조환자소채취적치료방식、료효급불량반응등차이。결과 A조진행술후보조화료적환자비례명현고우B조，차이유통계학의의（P<0.05）；년령재60~69세、자성격소수체음성급림파결전이양성시술후채취보조화료적영향인소（P<0.05）；A조적총유효솔고우B조，단차이무통계학의의（P>0.05）；량조균무엄중불량반응발생。결론년령재60~69세적유선암환자술후의채취보조화료，≥70세적유선암환자가채취내분비보조치료。
Objective To summarize the clinical characteristics of elderly patients with breast cancer, and to eval-uate the influences of adjuvant chemotherapy modality. Method A total of 178 cases of elderly breast cancer pa-tients were included in this study, and were grouped by age (60-69 or ≥70) as group A (103 cases), and group B (75 cases). The regimen, efficacy and adverse reactions of both groups were analyzed. Result There were more patients in group A who had underwent adjuvant chemotherapy compared with group B, and the difference was statistically significant (P<0.05); While age between 60-69, negative ER and positive lymph node metastasis were all significantly associated with postoperative adjuvant chemotherapy administration (P<0.05); Group A had higher yet insignificant overall response rate than that of group B (P>0.05); No serious adverse reactions were observed in either group. Con-clusion For patients of 60-69 years old, adjuvant chemotherapy is applicable, and for those who are over 70 years old, adjuvant endocrine therapy is recommended.