淮海医药
淮海醫藥
회해의약
Journal of Huaihai Medicine
2015年
6期
519-520,521
,共3页
乳腺肿瘤%相对表观扩散系数%扩散加权成像
乳腺腫瘤%相對錶觀擴散繫數%擴散加權成像
유선종류%상대표관확산계수%확산가권성상
Breast neoplasms%Relative apparent diffusion coefficient%Diffusion weighted imaging
目的:探讨相对表观扩散系数对乳腺良恶性病变的鉴别诊断价值。方法135例经病理证实的乳腺病变(恶性组44例,良性组91例)术前均行常规MR及DWI检查( b=0,800 s/mm2)。在ADC图的病变及同侧乳腺远隔正常腺体内绘制感兴趣区,测量ADC值并计算rADC值。采用两个独立样本t检验分析组间ADC值、rADC值的差异,并作ROC曲线分析。结果良、恶性组的ADC值分别为(1.45±0.22)×10-3 mm2/s、(1.03±0.19)×10-3 mm2/s (t=-10.89,P<0.05),rADC值分别为(0.72±0.08)×10-3mm2/s、(0.49±0.07)×10-3mm2/s(t=-15.35,P<0.05)。鉴别乳腺良恶性病变的ADC阈值为1.26×10-3 mm2/s,rADC阈值为0.62×10-3 mm2/s,敏感度、特异度及AUC分别为82.4%、95.5%、0.944;84.6%、90.9%、0.961。结论 ADC、rADC值可用于乳腺良恶性病变的鉴别诊断, rADC值的诊断敏感度及准确性更高。
目的:探討相對錶觀擴散繫數對乳腺良噁性病變的鑒彆診斷價值。方法135例經病理證實的乳腺病變(噁性組44例,良性組91例)術前均行常規MR及DWI檢查( b=0,800 s/mm2)。在ADC圖的病變及同側乳腺遠隔正常腺體內繪製感興趣區,測量ADC值併計算rADC值。採用兩箇獨立樣本t檢驗分析組間ADC值、rADC值的差異,併作ROC麯線分析。結果良、噁性組的ADC值分彆為(1.45±0.22)×10-3 mm2/s、(1.03±0.19)×10-3 mm2/s (t=-10.89,P<0.05),rADC值分彆為(0.72±0.08)×10-3mm2/s、(0.49±0.07)×10-3mm2/s(t=-15.35,P<0.05)。鑒彆乳腺良噁性病變的ADC閾值為1.26×10-3 mm2/s,rADC閾值為0.62×10-3 mm2/s,敏感度、特異度及AUC分彆為82.4%、95.5%、0.944;84.6%、90.9%、0.961。結論 ADC、rADC值可用于乳腺良噁性病變的鑒彆診斷, rADC值的診斷敏感度及準確性更高。
목적:탐토상대표관확산계수대유선량악성병변적감별진단개치。방법135례경병리증실적유선병변(악성조44례,량성조91례)술전균행상규MR급DWI검사( b=0,800 s/mm2)。재ADC도적병변급동측유선원격정상선체내회제감흥취구,측량ADC치병계산rADC치。채용량개독립양본t검험분석조간ADC치、rADC치적차이,병작ROC곡선분석。결과량、악성조적ADC치분별위(1.45±0.22)×10-3 mm2/s、(1.03±0.19)×10-3 mm2/s (t=-10.89,P<0.05),rADC치분별위(0.72±0.08)×10-3mm2/s、(0.49±0.07)×10-3mm2/s(t=-15.35,P<0.05)。감별유선량악성병변적ADC역치위1.26×10-3 mm2/s,rADC역치위0.62×10-3 mm2/s,민감도、특이도급AUC분별위82.4%、95.5%、0.944;84.6%、90.9%、0.961。결론 ADC、rADC치가용우유선량악성병변적감별진단, rADC치적진단민감도급준학성경고。
Objective To evaluate the value of rADC of diffusion weighted imaging to differential diagnosis of benign and malignant breast lesions.Methods 135 breast lesions, consisting of 44 malignant lesions and 91 benign lesions,underwent conventional MR and DWI ( b=0, 800 s/mm2 ) .The ADC of these lesions was measured.The rADC was equal to the lesion's ADC divided by the ADC of the ipsilateral normal breast tissue.The t-test was used for testing the difference of ADC values be-tween benign and malignant groups,as well as rADC.Threshold of ADC and rADC for differential diagnosis was acquired by ROC analysis.Results The ADC values of benign and malignant lesions were (1.45 ±0.22) ×10 -3 mm2/s and (1.03 ±0. 19) ×10 -3mm2/s(t=-10.89,P<0.05).The corresponding rADC values were (0.72 ±0.08) ×10 -3mm2/s and (0.49 ± 0.07) ×10 -3mm2/s(t=-15.35,P<0.05).The thresholds of ADC,rADC were 1.26 ×10 -3mm2/s,0.62 ×10 -3mm2/s. The sensitivity,specificity and AUC of ADC and rADC were 82.4%,95.5%,0.944;84.6%,90.9%,0.961.Conclusion ADC and rADC values have important values in differentiating benign and malignant breast lesions; especially rADC values have higher diagnostic sensitivity and accuracy.