中国社区医师
中國社區醫師
중국사구의사
Chinese Community Doctors
2015年
31期
59-60
,共2页
阿立哌唑%奥氮平%精神分裂症
阿立哌唑%奧氮平%精神分裂癥
아립고서%오담평%정신분렬증
Aripiprazole%Olanzapine%Schizophrenia
目的：探讨阿立哌唑和奥氮平治疗精神分裂症的临床疗效。方法：收治精神分裂症患者96例，根据治疗药物的不同将其分为 A 组和 B 组，A 组给予奥氮平，B 组给予阿立哌唑，分别于治疗前、治疗8周后分析两组患者的PANSS评分、生活质量评分，观察两组患者的血清催乳素水平。结果：两组患者治疗后PANSS评分和明显低于治疗前；两组患者治疗后生活质量分明显低于治疗前。两组患者的血清催乳素(PRL)较治疗前均有所上升，A组的上升幅度明显高于B组(P＜0.05)。结论：两种治疗精神分裂症的药物的疗效相当，但是阿立哌唑对患者的PRL影响较小。
目的：探討阿立哌唑和奧氮平治療精神分裂癥的臨床療效。方法：收治精神分裂癥患者96例，根據治療藥物的不同將其分為 A 組和 B 組，A 組給予奧氮平，B 組給予阿立哌唑，分彆于治療前、治療8週後分析兩組患者的PANSS評分、生活質量評分，觀察兩組患者的血清催乳素水平。結果：兩組患者治療後PANSS評分和明顯低于治療前；兩組患者治療後生活質量分明顯低于治療前。兩組患者的血清催乳素(PRL)較治療前均有所上升，A組的上升幅度明顯高于B組(P＜0.05)。結論：兩種治療精神分裂癥的藥物的療效相噹，但是阿立哌唑對患者的PRL影響較小。
목적：탐토아립고서화오담평치료정신분렬증적림상료효。방법：수치정신분렬증환자96례，근거치료약물적불동장기분위 A 조화 B 조，A 조급여오담평，B 조급여아립고서，분별우치료전、치료8주후분석량조환자적PANSS평분、생활질량평분，관찰량조환자적혈청최유소수평。결과：량조환자치료후PANSS평분화명현저우치료전；량조환자치료후생활질량분명현저우치료전。량조환자적혈청최유소(PRL)교치료전균유소상승，A조적상승폭도명현고우B조(P＜0.05)。결론：량충치료정신분렬증적약물적료효상당，단시아립고서대환자적PRL영향교소。
Objective:To explore the clinical curative effect of aripiprazole and olanzapine in the treatment of schizophrenia. Methods:96 patients with schizophrenia were selected.According to the different treatment drugs,they were divided into A group and B group.A group was given olanzapine,B group was given aripiprazole.Before treatment and after treatment for 8 weeks,the PANSS scores,life quality scores of two groups were analyzed.The serum prolactin levels of two groups were observed.Results:The PANSS scores of two groups after treatment were significantly lower than those before treatment.The life quality scores of two groups after treatment were significantly lower than those before treatment.The serum prolactin(PRL) of two groups were increased than before treatment,the rising range of A group was significantly higher than that of B group(P<0.05).Conclusion:The curative effects of two drugs in the treatment of schizophrenia are comparative,but aripiprazole has a smaller effect on the PRL of patients.
