CAJ | 학술논문

探讨红甜菜水提物对小鼠失血性贫血的影响。将50只小鼠随机分成正常对照组、模型组和红甜菜水提物高、中、低剂量组，每组10只。以小鼠内眦静脉丛取血法，建立小鼠失血性贫血模型，24 h后开始灌胃给药，对照组灌胃蒸馏水。分别在失血前、失血24 h后、给药5 d和10 d后测定小鼠的红细胞数和血红蛋白含量。造模使小鼠红细胞数减少，血红蛋白含量降低；红甜菜水提物灌胃处理后，小鼠红细胞数和血红蛋白含量均有不同程度的升高，用红甜菜水提物灌胃5d后，高剂量组小鼠的血红蛋白含量和红细胞数与对照组相比有显著差异，明显高于对照组；灌胃10 d后，红甜菜水提物高、中剂量组小鼠的两项指标均恢复正常。红甜菜水提物对失血性贫血的恢复有促进作用。
탐토홍첨채수제물대소서실혈성빈혈적영향。장50지소서수궤분성정상대조조、모형조화홍첨채수제물고、중、저제량조，매조10지。이소서내자정맥총취혈법，건립소서실혈성빈혈모형，24 h후개시관위급약，대조조관위증류수。분별재실혈전、실혈24 h후、급약5 d화10 d후측정소서적홍세포수화혈홍단백함량。조모사소서홍세포수감소，혈홍단백함량강저；홍첨채수제물관위처리후，소서홍세포수화혈홍단백함량균유불동정도적승고，용홍첨채수제물관위5d후，고제량조소서적혈홍단백함량화홍세포수여대조조상비유현저차이，명현고우대조조；관위10 d후，홍첨채수제물고、중제량조소서적량항지표균회복정상。홍첨채수제물대실혈성빈혈적회복유촉진작용。
To investigate the effects of aqueous extract of the red beet on loss anemia mice , the 50 mice were randomly divided into normal control group , model group and red beet water extract high , medium and low dose groups, each group contained 10 mice. The blood loss anemia mice model was constructed by the method of angular vein plexus. Gastric perfusion was started after 24 hours , whereas the mice in the control group were given the distilled water in the gastric. The number of red blood cells in mice and hemoglobin content were determined before the loss of blood, blood loss after 24 hours, after dosing 5 days and 10 days, respectively. Our model reduced the number of red blood cells in mice , and decreased the content of hemoglobin. After treated by the aqueous extract of red beet orally , the red blood cell count and hemoglobin content of mice increased variously. After gavaging 5 days with red beet aqueous extract , there was significant difference between the hemoglobin content, red blood cell count of the high dose group and the control group. The former group was significantly higher than those in control group. Red beet aqueous extract of high , middle dose group mice returned to normal after 10 days of gavaging. Aqueous extract of red beet hemorrhagic anemia could promote recovery.