临床合理用药杂志
臨床閤理用藥雜誌
림상합리용약잡지
Chinese Journal of Clinical Rational Drug Use
2015年
30期
3-4
,共2页
糖尿病,2 型%诺和锐 30%诺和灵 30R%治疗结果
糖尿病,2 型%諾和銳 30%諾和靈 30R%治療結果
당뇨병,2 형%낙화예 30%낙화령 30R%치료결과
Diabetes mellitus,type 2%NovoMix 30%Novolin 30R%Treatment outcome
目的：探讨诺和锐30与诺和灵30R 治疗初诊2型糖尿病患者的临床疗效及安全性。方法选取2013年6月—2014年12月成都市新都区人民医院收治的初诊2型糖尿病患者100例，按随机数字表法将其分为Ⅰ组与Ⅱ组，各50例。Ⅰ组患者于早晚餐前皮下注射诺和锐30治疗，Ⅱ组患者于早晚餐前皮下注射诺和灵30R 治疗。观察两组患者治疗前后糖化血红蛋白（HbA1c ）、空腹血糖（FPG）、餐后2h 血糖（2hPG）水平及低血糖发生情况。结果治疗前两组患者 HbA1c、FPG、2hPG 水平比较，差异无统计学意义（P >0.05）；治疗后Ⅰ组患者2hPG 水平低于Ⅱ组，低血糖发生率低于Ⅱ组，差异有统计学意义（P <0.05）。结论诺和锐30治疗初诊2型糖尿病患者的临床疗效显著，可降低患者低血糖的发生风险。
目的：探討諾和銳30與諾和靈30R 治療初診2型糖尿病患者的臨床療效及安全性。方法選取2013年6月—2014年12月成都市新都區人民醫院收治的初診2型糖尿病患者100例，按隨機數字錶法將其分為Ⅰ組與Ⅱ組，各50例。Ⅰ組患者于早晚餐前皮下註射諾和銳30治療，Ⅱ組患者于早晚餐前皮下註射諾和靈30R 治療。觀察兩組患者治療前後糖化血紅蛋白（HbA1c ）、空腹血糖（FPG）、餐後2h 血糖（2hPG）水平及低血糖髮生情況。結果治療前兩組患者 HbA1c、FPG、2hPG 水平比較，差異無統計學意義（P >0.05）；治療後Ⅰ組患者2hPG 水平低于Ⅱ組，低血糖髮生率低于Ⅱ組，差異有統計學意義（P <0.05）。結論諾和銳30治療初診2型糖尿病患者的臨床療效顯著，可降低患者低血糖的髮生風險。
목적：탐토낙화예30여낙화령30R 치료초진2형당뇨병환자적림상료효급안전성。방법선취2013년6월—2014년12월성도시신도구인민의원수치적초진2형당뇨병환자100례，안수궤수자표법장기분위Ⅰ조여Ⅱ조，각50례。Ⅰ조환자우조만찬전피하주사낙화예30치료，Ⅱ조환자우조만찬전피하주사낙화령30R 치료。관찰량조환자치료전후당화혈홍단백（HbA1c ）、공복혈당（FPG）、찬후2h 혈당（2hPG）수평급저혈당발생정황。결과치료전량조환자 HbA1c、FPG、2hPG 수평비교，차이무통계학의의（P >0.05）；치료후Ⅰ조환자2hPG 수평저우Ⅱ조，저혈당발생솔저우Ⅱ조，차이유통계학의의（P <0.05）。결론낙화예30치료초진2형당뇨병환자적림상료효현저，가강저환자저혈당적발생풍험。
Objective To explore the clinical efficacy and safety of NovoMix 30 and Novolin 30R in the treatment of patients with newly diagnosed type 2 diabetes. Methods A total of 100 patients with newly diagnosed type 2 diabetes were se-lected in the People's Hospital of Xindu District from June 2013 to December 2014,according to random number table,they were divided into Ⅰ group and Ⅱ group,50 cases in each group. Ⅰ group were given NovoMix 30 treatment,Ⅱ group were given Novolin 30R treatment. Before and after treatment,glycosylated hemoglobin(HbA1c ),fasting plasma glucose(FPG),2 hour postprandial plasma glucose(2hPG)levels and occurrence of hypoglycaemia between the two groups were compared. Re-sults Before treatment,HbA1c ,FPG,2hPG levels showed no significant differences between the two groups(P > 0. 05),af-ter treatment,2hPG level of Ⅰ group was lower than that of Ⅱ group,incidence of hypoglycemia of Ⅰ group was lower than that of Ⅱ group(P < 0. 05). Conclusion NovoMix 30 has notable curative effect in the treatment of patients with newly diag-nosed type 2 diabetes,can reduce the risk of hypoglycaemia.
