食品研究与开发
食品研究與開髮
식품연구여개발
Food Research and Development
2015年
20期
17-19
,共3页
齐炳理%张兴昌%孙婷%陈世贤
齊炳理%張興昌%孫婷%陳世賢
제병리%장흥창%손정%진세현
植物乳杆菌%发酵乳%高脂血症
植物乳桿菌%髮酵乳%高脂血癥
식물유간균%발효유%고지혈증
Lactobacillus plantarum%fermented milk%hyperlipidemia
为了探讨植物乳杆菌发酵乳对实验性高脂血症大鼠血脂代谢的调节作用，为功能性发酵乳制品开发提供实验参考。采用高脂饲料喂养法，诱导形成大鼠高脂血症模型，将造模成功大鼠随机分为3组：高脂模型组、发酵乳样品组和自然降脂组。高脂模型组继续饲喂高脂饲料作为对照，发酵乳样品组饲喂高脂饲料的同时灌胃植物乳杆菌发酵乳，自然降脂组改为饲喂基础饲料，4周后测定各组大鼠的血脂浓度。结果显示，发酵乳样品组及自然降脂组与高脂模型组相比较，大鼠血清总胆固醇（TC）浓度显著下降（P<0.01），血清低密度脂蛋白胆固醇（LDL-C）浓度显著下降（P<0.01），血清高密度脂蛋白胆固醇（HDL-C）浓度升高（P<0.05），表明发酵乳样品对高脂血症大鼠血脂具有显著改善作用，通过调节饮食结构，高脂血症大鼠血脂可自行恢复正常。
為瞭探討植物乳桿菌髮酵乳對實驗性高脂血癥大鼠血脂代謝的調節作用，為功能性髮酵乳製品開髮提供實驗參攷。採用高脂飼料餵養法，誘導形成大鼠高脂血癥模型，將造模成功大鼠隨機分為3組：高脂模型組、髮酵乳樣品組和自然降脂組。高脂模型組繼續飼餵高脂飼料作為對照，髮酵乳樣品組飼餵高脂飼料的同時灌胃植物乳桿菌髮酵乳，自然降脂組改為飼餵基礎飼料，4週後測定各組大鼠的血脂濃度。結果顯示，髮酵乳樣品組及自然降脂組與高脂模型組相比較，大鼠血清總膽固醇（TC）濃度顯著下降（P<0.01），血清低密度脂蛋白膽固醇（LDL-C）濃度顯著下降（P<0.01），血清高密度脂蛋白膽固醇（HDL-C）濃度升高（P<0.05），錶明髮酵乳樣品對高脂血癥大鼠血脂具有顯著改善作用，通過調節飲食結構，高脂血癥大鼠血脂可自行恢複正常。
위료탐토식물유간균발효유대실험성고지혈증대서혈지대사적조절작용，위공능성발효유제품개발제공실험삼고。채용고지사료위양법，유도형성대서고지혈증모형，장조모성공대서수궤분위3조：고지모형조、발효유양품조화자연강지조。고지모형조계속사위고지사료작위대조，발효유양품조사위고지사료적동시관위식물유간균발효유，자연강지조개위사위기출사료，4주후측정각조대서적혈지농도。결과현시，발효유양품조급자연강지조여고지모형조상비교，대서혈청총담고순（TC）농도현저하강（P<0.01），혈청저밀도지단백담고순（LDL-C）농도현저하강（P<0.01），혈청고밀도지단백담고순（HDL-C）농도승고（P<0.05），표명발효유양품대고지혈증대서혈지구유현저개선작용，통과조절음식결구，고지혈증대서혈지가자행회복정상。
The objective of this study was to investigate the effect of milk product fermented by Lactobacillus plantarum on blood lipids in hyperlipidemia rat and to provide experimental date for develeping functional fermented dairy product. The hyperlipidemia rat model was induced by high fat diet successfully and then the rats were randomly divided into 3 group:hyperlipidemia group, fermented milk group and the untreated group. The hyperlipidemia group were still fed high fat diet as control , the fermented milk group were fed not only high fat diet but also milk product fermented by Lactobacillus plantarum by gastric gavage and the untreated group changed to be fed basic diet. The blood lipids concentrations of each group were determined after a 4 weeks feeding period. The results showed that the concentrations of serum total cholesterol (TC) and low density lipoprotein-cholesterol (LDL-C) of the fermented milk group and the untreated group decreased significantly (P<0.01), also the concentrations of serum high density lipoprotein-cholesterol (HDL-C) of the fermented milk group and the untreated group increased significantly (P<0.05) compared with hyperlipidemia group. The present results indicated that the milk product fermented by Lactobacillus plantarum could improve blood lipids in hyperlipidemia rat, and the blood lipids in hyperlipidemia rat can recover naturally by improving diet structure.
