西北药学杂志
西北藥學雜誌
서북약학잡지
Northwest Pharmaceutical Journal
2015年
6期
674-678,679
,共6页
苦豆草%总生物碱%大孔吸附树脂%纯化
苦豆草%總生物堿%大孔吸附樹脂%純化
고두초%총생물감%대공흡부수지%순화
Sophora alopecuroides L .%total alkaloids%macroporous adsorption resin%purification
目的：采用大孔树脂分离纯化苦豆草总生物碱，优选最佳工艺条件。方法以苦豆草总生物碱的吸附量及解吸率为评价指标，比较DF01、D101等8种型号大孔树脂对苦豆草总生物碱的分离纯化性能，选出最佳树脂并优选纯化工艺。结果 D101型大孔树脂对苦豆草总生物碱具有较好的吸附分离性能，在实验条件下对苦豆草总生物碱的吸附量和解吸率可达到9．2 mg · mL －1和90％以上。结论该优选工艺可为苦豆草总生物碱纯化的产业化生产提供依据。
目的：採用大孔樹脂分離純化苦豆草總生物堿，優選最佳工藝條件。方法以苦豆草總生物堿的吸附量及解吸率為評價指標，比較DF01、D101等8種型號大孔樹脂對苦豆草總生物堿的分離純化性能，選齣最佳樹脂併優選純化工藝。結果 D101型大孔樹脂對苦豆草總生物堿具有較好的吸附分離性能，在實驗條件下對苦豆草總生物堿的吸附量和解吸率可達到9．2 mg · mL －1和90％以上。結論該優選工藝可為苦豆草總生物堿純化的產業化生產提供依據。
목적：채용대공수지분리순화고두초총생물감，우선최가공예조건。방법이고두초총생물감적흡부량급해흡솔위평개지표，비교DF01、D101등8충형호대공수지대고두초총생물감적분리순화성능，선출최가수지병우선순화공예。결과 D101형대공수지대고두초총생물감구유교호적흡부분리성능，재실험조건하대고두초총생물감적흡부량화해흡솔가체도9．2 mg · mL －1화90％이상。결론해우선공예가위고두초총생물감순화적산업화생산제공의거。
Objective To find out the suitable process conditions for separation and purification of total alkaloids of Sophora alope‐curoides L .by using macroporous resin .Methods The separation and purification performance of 8 types of macroporous resins , such as DF01 and D101 was compared .The adsorption capacity and desorption rate of the total alkaloids of Sophora alopecuroides L .,were used as an evaluation index .Results Under the experimental conditions ,the separation and adsorption performance of D101 was better than other types of macroporous resins ,for which the adsorption capacity and desorption rate of the total alkaloids was reached to 9 .2 mg · mL -1 and more than 90% ,respectively .Conclusion This result provides the basis for the industrial puri‐fication of the total alkaloids from Sophora alopecuroidesL .
