CAJ | 학술논문

目的：研究泰国葛根的化学成分。方法泰国葛根样品用正己烷提取除杂后，药渣用乙酸乙酯提取，得到的滤液浓缩后，用甲醇提取得到精制乙酸乙酯部位；乙酸乙酯提取后的药渣用甲醇提取，浓缩后再用正丁醇萃取得正丁醇部位；利用正相硅胶、MDS‐5等常规柱色谱技术分离得到单体化合物，根据其理化性质及波谱学数据鉴定其化学结构。结果分离得到5个单体化合物，分别被鉴定为Mirificoumestan（1），十七烷酸（2），去氧葛雌素（3），葛根素（4），大豆苷（5）。结论化合物2是首次从该植物中分离得到。
목적：연구태국갈근적화학성분。방법태국갈근양품용정기완제취제잡후，약사용을산을지제취，득도적려액농축후，용갑순제취득도정제을산을지부위；을산을지제취후적약사용갑순제취，농축후재용정정순췌취득정정순부위；이용정상규효、MDS‐5등상규주색보기술분리득도단체화합물，근거기이화성질급파보학수거감정기화학결구。결과분리득도5개단체화합물，분별피감정위Mirificoumestan（1），십칠완산（2），거양갈자소（3），갈근소（4），대두감（5）。결론화합물2시수차종해식물중분리득도。
Objective To study the chemical constituents of Puerariamirifica .Methods Puerariamirifica was extracted with n‐hexane to remove impurity ,then the filtrate and residue were extracted with methanol ,and the concentrated solutions were extrac‐ted with ethyl acetate and n‐butyl alcohol ,respectively .The compounds were isolated and obtained by column chromatography in‐cluding silica gel and MDS‐5 . Their structures were elucidated by means of physiochemical properties and spectral analysis . Results 5 compounds were isolated from Pueraria miri f ica .And their structures were elucidated as :mirificoumestan(1) ,hepta‐decanoic acid(2) ,deoxymiroestrol (3) ,puerarin (4) ,and daidzin(5) ,respectively .Conclusion Compound 2 was isolated from this plant for the first time .