CAJ | 학술논문

目的分析2014年首都医科大学附属北京中医医院产β-内酰胺酶金黄色葡萄球菌的分布特点及耐药性. 方法收集送检标本15 620例,对产β-内酰胺酶金黄色葡萄球菌进行分离,观察其临床分布特征及耐药性. 结果共分离非重复病原菌5075株,其中金黄色葡萄球菌526株(10. 4%),包括产β-内酰胺酶金黄色葡萄球菌301株(57. 2%),其来源主要为创口分泌液和痰液,分布科室主要有重症监护病房、皮肤科和疮疡外科,对青霉素、红霉素、环丙沙星和苯唑西林等耐药率较高,对呋喃妥因、利奈唑胺和万古霉素的耐药率均为0;多引起呼吸机相关感染、下呼吸道感染和皮肤化脓性感染等. 结论产β-内酰胺酶金黄色葡萄球菌分布广泛,其对多种抗生素耐药率高,临床应高度重视.
목적 분석2014년수도의과대학부속북경중의의원산β-내선알매금황색포도구균적분포특점급내약성. 방법 수집송검표본15 620례,대산β-내선알매금황색포도구균진행분리,관찰기림상분포특정급내약성. 결과 공분리비중복병원균5075주,기중금황색포도구균526주(10. 4%),포괄산β-내선알매금황색포도구균301주(57. 2%),기래원주요위창구분비액화담액,분포과실주요유중증감호병방、피부과화창양외과,대청매소、홍매소、배병사성화분서서림등내약솔교고,대부남타인、리내서알화만고매소적내약솔균위0;다인기호흡궤상관감염、하호흡도감염화피부화농성감염등. 결론 산β-내선알매금황색포도구균분포엄범,기대다충항생소내약솔고,림상응고도중시.
Objective To analyze the characteristics of distribution and drug resistance of staphylococcus aureus producingβ-lactamase in Beijing TCM Hospital affiliated to the Capital Medical University in 2014. Methods A total of 15 620 samples were collected, and the staphylococcus aureus producingβ-lactamase were isolated, and then the charac-teristics of clinical distribution and drug resistance were observed. Results A total of 5075 bacterium strains were isola-ted, including 526 strains ( 10. 4%) of staphylococcus aureus, 301 strains ( 57. 2%) of staphylococcus aureus producingβ-lactamase. The staphylococcus aureus producingβ-lactamase were mainly from wound secretion and sputum, and were mainly distributed in ICU, dermatology department and department of sores ulceration surgery. The staphylococ-cus aureus producing β-lactamase had a high rate of drug resistance against Penicillin, Erythromycin, Ciprofloxacin and Oxacillin, but had 0% drug resistance rate against Nitrofurantoin, Linezolid and Vancomycin. The staphylococcus aureus producing β-lactamase could probably cause ventilator associated infections, lower respiratory tract infections, purulent skin infections, etc. Conclusion Staphylococcus aureus producingβ-lactamase is widely distributed, and has high rates of drug resistance against many antibiotics. So clinicians should pay more attention to it.