武警医学
武警醫學
무경의학
Medical Journal of the Chinese People's Armed Police Forces
2015年
9期
900-903
,共4页
剖宫产%子宫瘢痕%CD34
剖宮產%子宮瘢痕%CD34
부궁산%자궁반흔%CD34
cesarean section%uterine scar%CD34
目的：了解子宫下段剖宫产术后不同年限子宫瘢痕的组织学与力学特征。方法收集2011－01到2013－12期间二次剖宫产病例。根据剖宫产术后间隔年限分为两组：短期组，前次剖宫产术日与二次剖宫产术日间隔＞1年且≤2年；长期组，间隔＞2年且≤5年。排除子宫瘢痕部位肌不连等切口愈合不良的病例。观察二次剖宫产前子宫下段厚度、肌肉与血管排列结构、胶原含量与子宫瘢痕组织抗拉强度。结果短期组与长期组子宫下段瘢痕部位超声检测厚度[（2．9±0．9）mm vs （3．3±0．6） mm]，与离体测量厚度[（3．6±1．3）mm vs （4．2±1．2） mm]，两组比较差异无统计学意义；子宫瘢痕部位肌肉（抗人β－actin单克隆抗体免疫染色）与胶原排列紊乱；短期组子宫瘢痕组织内胶原含量（39．3±7．1）μg／mg，显著高于长期组（33．3±7．6）μg／mg，P＝0．022；但瘢痕组织的抗拉强度并无统计学差异。结论剖宫产术后不同年限子宫瘢痕的组织学与力学特征，并无统计学差异，但应尽量减少子宫伤口愈合不良。
目的：瞭解子宮下段剖宮產術後不同年限子宮瘢痕的組織學與力學特徵。方法收集2011－01到2013－12期間二次剖宮產病例。根據剖宮產術後間隔年限分為兩組：短期組，前次剖宮產術日與二次剖宮產術日間隔＞1年且≤2年；長期組，間隔＞2年且≤5年。排除子宮瘢痕部位肌不連等切口愈閤不良的病例。觀察二次剖宮產前子宮下段厚度、肌肉與血管排列結構、膠原含量與子宮瘢痕組織抗拉彊度。結果短期組與長期組子宮下段瘢痕部位超聲檢測厚度[（2．9±0．9）mm vs （3．3±0．6） mm]，與離體測量厚度[（3．6±1．3）mm vs （4．2±1．2） mm]，兩組比較差異無統計學意義；子宮瘢痕部位肌肉（抗人β－actin單剋隆抗體免疫染色）與膠原排列紊亂；短期組子宮瘢痕組織內膠原含量（39．3±7．1）μg／mg，顯著高于長期組（33．3±7．6）μg／mg，P＝0．022；但瘢痕組織的抗拉彊度併無統計學差異。結論剖宮產術後不同年限子宮瘢痕的組織學與力學特徵，併無統計學差異，但應儘量減少子宮傷口愈閤不良。
목적：료해자궁하단부궁산술후불동년한자궁반흔적조직학여역학특정。방법수집2011－01도2013－12기간이차부궁산병례。근거부궁산술후간격년한분위량조：단기조，전차부궁산술일여이차부궁산술일간격＞1년차≤2년；장기조，간격＞2년차≤5년。배제자궁반흔부위기불련등절구유합불량적병례。관찰이차부궁산전자궁하단후도、기육여혈관배렬결구、효원함량여자궁반흔조직항랍강도。결과단기조여장기조자궁하단반흔부위초성검측후도[（2．9±0．9）mm vs （3．3±0．6） mm]，여리체측량후도[（3．6±1．3）mm vs （4．2±1．2） mm]，량조비교차이무통계학의의；자궁반흔부위기육（항인β－actin단극륭항체면역염색）여효원배렬문란；단기조자궁반흔조직내효원함량（39．3±7．1）μg／mg，현저고우장기조（33．3±7．6）μg／mg，P＝0．022；단반흔조직적항랍강도병무통계학차이。결론부궁산술후불동년한자궁반흔적조직학여역학특정，병무통계학차이，단응진량감소자궁상구유합불량。
Objective To study the histological and mechanical characteristics of cesarean uterine scar in different years post cesarean section ( CS) .Methods Patients were set into two groups according to the interval years post CS .Group 1:the interval peri-ods between the two CS operation day were >1 year and ≤2 years;Group 2:interval >2 years and ≤5 years.Thickness of the LUS was detected by transabdominal ultrasound scan ( TAUS ) before CS and micrometer screw gauge once the samples of LUS were ob-tained.Arrangement of muscles (anti-β-actin) and blood vessels (anti-CD34) by immunohistochemistry, tensile strength of the uter-ine scar tissue were detected as well .Results The thickness of LUS scar were consistent between the groups , no matter what methods were used;muscle and collagen in the uterine scar were disorderly under optical microscopy , collagen content within “Group 1” (39.3 ±7.1) μg/mg, was significantly higher than “Group 2” (33.3 ±7.6) μg/mg, P=0.022;there were no significant differences be-tween the tensile strength of the scar tissue .Conclusions The histological and mechanical characteristics of the anterior wall scar of LUS show no significant difference between less or more than 2 years, which needs strenuous efforts to avoid poor uterine wound heal-ing.
