解放军医药杂志
解放軍醫藥雜誌
해방군의약잡지
Medical & Pharmaceutical Journal of Chinese People's Liberation Army
2015年
10期
42-46
,共5页
张懿行%徐飚%王伟炳%沈鑫%李朋%王沛%李小攀
張懿行%徐飚%王偉炳%瀋鑫%李朋%王沛%李小攀
장의행%서표%왕위병%침흠%리붕%왕패%리소반
结核,肺%死亡原因%危险因素%流行病学研究
結覈,肺%死亡原因%危險因素%流行病學研究
결핵,폐%사망원인%위험인소%류행병학연구
Tuberculosis%pulmonary%Cause of death%Risk factors%Epidemiologic studies
目的 探讨上海市浦东新区居民肺结核死亡相关危险因素. 方法 应用Kaplan-Meier法、Log-rank检验和Cox多元回归模型对2004年1月1日—2008年12月31日确诊的肺结核1570例的年龄、性别、发病类型、首次痰涂片结果、合并疾病、病变范围、耐药情况等对肺结核死亡的影响进行分析. 结果 单因素分析结果显示,年龄≥60岁、男性、首次痰涂片结果阳性、复治、诊断延误、病变≥3个肺野、耐多药、合并其他疾病是肺结核患者死亡的危险因素(P<0. 05,P<0. 01). 多因素Cox多元回归模型分析表明,年龄、性别、首次痰涂片结果、治疗分类、病变范围、合并其他疾病是肺结核患者死亡的相关危险因素(P<0. 05). 结论 对老年、男性、首次痰涂片结果阳性、复治、病变范围大、合并其他疾病的肺结核患者采取相应的防治措施,可能会降低肺结核患者的病死率.
目的 探討上海市浦東新區居民肺結覈死亡相關危險因素. 方法 應用Kaplan-Meier法、Log-rank檢驗和Cox多元迴歸模型對2004年1月1日—2008年12月31日確診的肺結覈1570例的年齡、性彆、髮病類型、首次痰塗片結果、閤併疾病、病變範圍、耐藥情況等對肺結覈死亡的影響進行分析. 結果 單因素分析結果顯示,年齡≥60歲、男性、首次痰塗片結果暘性、複治、診斷延誤、病變≥3箇肺野、耐多藥、閤併其他疾病是肺結覈患者死亡的危險因素(P<0. 05,P<0. 01). 多因素Cox多元迴歸模型分析錶明,年齡、性彆、首次痰塗片結果、治療分類、病變範圍、閤併其他疾病是肺結覈患者死亡的相關危險因素(P<0. 05). 結論 對老年、男性、首次痰塗片結果暘性、複治、病變範圍大、閤併其他疾病的肺結覈患者採取相應的防治措施,可能會降低肺結覈患者的病死率.
목적 탐토상해시포동신구거민폐결핵사망상관위험인소. 방법 응용Kaplan-Meier법、Log-rank검험화Cox다원회귀모형대2004년1월1일—2008년12월31일학진적폐결핵1570례적년령、성별、발병류형、수차담도편결과、합병질병、병변범위、내약정황등대폐결핵사망적영향진행분석. 결과 단인소분석결과현시,년령≥60세、남성、수차담도편결과양성、복치、진단연오、병변≥3개폐야、내다약、합병기타질병시폐결핵환자사망적위험인소(P<0. 05,P<0. 01). 다인소Cox다원회귀모형분석표명,년령、성별、수차담도편결과、치료분류、병변범위、합병기타질병시폐결핵환자사망적상관위험인소(P<0. 05). 결론 대노년、남성、수차담도편결과양성、복치、병변범위대、합병기타질병적폐결핵환자채취상응적방치조시,가능회강저폐결핵환자적병사솔.
Objective To investigate the risk factors of death of tuberculosis ( TB) patients in Pudong New Area in Shanghai. Methods A total of TB 1570 patients diagnosed from January 1, 2004 to December 31, 2008 were recrui-ted in this study, and the effects of age, gender, pathogenesy types, results of first sputum smear, other combined disea-ses and drug resistance on the death induced by TB were analyzed using Kaplan-Meier method, Log-rank test and Cox multivariate regression model. Results The result of single factor analysis showed that male patients more than 60 years old with positive result of first sputum smear, retreatment, delaying diagnosis and treatment, lesions range equal to or more than 3 lung fields, multiple drug resistant pulmonary tuberculosis and other combined diseases were the risk factors of death of TB patients (P<0. 05, P<0. 01). The result of Cox multivariate regression analysis showed that age, gen-der, result of first sputum smear, treatment methods, lesions range and other combined diseases were the risk factors of death of TB patients (P<0. 05). Conclusion Related measures can be given to the male elderly TB patients with posi-tive result of first sputum smear, retreatment, large lesions range and other combined diseases, which may reduce the mortality rate of TB patients.
