CAJ | 학술논문

目的：利用经颅多普勒超声（TCD）评估老年颅内外动脉狭窄的相关危险因素。方法选择 TCD筛查、并经其他影像检查确诊的颅内外动脉狭窄患者299例，分为老年组（≥60岁）200例和非老年组（40～59岁）99例，记录血管疾病相关病史，分析各危险因素的影响特点。结果老年组前循环狭窄发生率低于非老年组（66.5％ v s 82.8％，P＝0．002），前后循环狭窄发生率高于非老年组（14．0％ v s 4．0％，P＝0．005），颅内外动脉狭窄发生率高于非老年组（9．0％ v s 3．0％，P＝0．043）。老年组与非老年组大脑中动脉狭窄发生率比较无显著差异（74．0％ v s 72.7％，P＝0.459）。高血压、糖尿病、高脂血症、吸烟、心脑血管危险因素家族史是老年颅内外动脉狭窄的独立危险因素（ P＝0．000）。结论老年颅内外动脉和前后循环狭窄发生率明显增高，存在长期吸烟、高血压、糖尿病、高脂血症及有心脑血管病危险因素家族史等患者应常规进行T CD检测。
목적：이용경로다보륵초성（TCD）평고노년로내외동맥협착적상관위험인소。방법선택 TCD사사、병경기타영상검사학진적로내외동맥협착환자299례，분위노년조（≥60세）200례화비노년조（40～59세）99례，기록혈관질병상관병사，분석각위험인소적영향특점。결과노년조전순배협착발생솔저우비노년조（66.5％ v s 82.8％，P＝0．002），전후순배협착발생솔고우비노년조（14．0％ v s 4．0％，P＝0．005），로내외동맥협착발생솔고우비노년조（9．0％ v s 3．0％，P＝0．043）。노년조여비노년조대뇌중동맥협착발생솔비교무현저차이（74．0％ v s 72.7％，P＝0.459）。고혈압、당뇨병、고지혈증、흡연、심뇌혈관위험인소가족사시노년로내외동맥협착적독립위험인소（ P＝0．000）。결론노년로내외동맥화전후순배협착발생솔명현증고，존재장기흡연、고혈압、당뇨병、고지혈증급유심뇌혈관병위험인소가족사등환자응상규진행T CD검측。
Objective To assess the intracranial and extracranial artery stenosis and its risk factors in elderly patients by TCD ultrasonography .Methods Two hundred and ninety‐nine patients with TCD ultrasonography‐confirmed intracranial and extracranial artery stenosis were divided in‐to ≥60 years old group (n=200)and 40-59 years old group (n=99) .The risk factors for vascu‐lar diseases were compared between the two groups .Results The incidence of anterior circulation stenosis was significantly lower while that of anterior‐posterior circulation stenosis was signifi‐cantly higher in ≥60 years old group than in 40-59 years old group (66 .5% vs 82 .8% ;14 .0% vs 4 .0% ,P<0 .01) .The incidence of intracranial and extracranial artery stenosis was significantly higher in ≥60 years old group than in 40 -59 years old group (9 .0% vs 3 .0% ,P=0 .043) .No significant difference was found in the incidence of MCA stenosis between the two groups .That hypertension ,diabetes ,hyperlipemia ,smoking and family history of cardio‐cerebrovascular disease were the independent risk factors for intracranial artery stenosis in elderly patients .Conclusion The incidence of intracranial and extracranial artery stenosis and anterior‐posterior circulation ste‐nosis is significantly higher in elderly subjects than in non‐elderly subjects .Conventional TCD ul‐trasonography is necessary for those with a history of smoking ,hypertension ,diabetes ,hyper‐lipemia and a family history of cardio‐cerebrovascular disease .