CAJ | 학술논문

目的：探讨新诊断2型糖尿病患者血清胱抑素C（CysC）与冠状动脉病变支数的关系。方法2009年—2012年在我院内分泌科住院的新诊断2型糖尿病患者64例，根据320-DVCT中冠状动脉病变支数将患者分为3组：无病变组（A组，n=16）、单支病变组（B组，n=21）、多支病变组（C组，n=27）。比较3组间血清CysC的差异。结果血清CysC在A、B、C组分别是（0.62±0.28）mg/L、（1.16±0.50）mg/L、（1.52±0.69）mg/L，3组血清CysC水平有显著性差异（P<0.05）。结论新诊断2型糖尿病患者血清CysC水平与冠状动脉病变支数间呈正相关。
목적：탐토신진단2형당뇨병환자혈청광억소C（CysC）여관상동맥병변지수적관계。방법2009년—2012년재아원내분비과주원적신진단2형당뇨병환자64례，근거320-DVCT중관상동맥병변지수장환자분위3조：무병변조（A조，n=16）、단지병변조（B조，n=21）、다지병변조（C조，n=27）。비교3조간혈청CysC적차이。결과혈청CysC재A、B、C조분별시（0.62±0.28）mg/L、（1.16±0.50）mg/L、（1.52±0.69）mg/L，3조혈청CysC수평유현저성차이（P<0.05）。결론신진단2형당뇨병환자혈청CysC수평여관상동맥병변지수간정정상관。
ObjectiveTo investigate the relationship between serum cystatin C(CysC)and the number of diseased coronary artery in newly diagnosed type 2 diabetes mellitus(T2DM)patients.MethodsAccording to the number of diseased coronary artery measured by 320-DVCT,a total of 64 newly diagnosed T2DM patients visited in our department of endocrinology from 2009 to 2012 were divided into three groups:no coronary artery lesion group (group A, n=16),one coronary artery lesion group(group B,n=21),multiple coronary artery lesion group(group C,n=27). CysC were compared.ResultsSerum CysC in A,B,C group were(0.62±0.28)mg/L,(1.16±0.50)mg/L,(1.52±0.69) mg/L. There were significant difference among the groups(P<0.05).ConclusionsThere was a significantly positive correlation between serum cystatin C and the number of diseased coronary artery in newly diagnosed T2DM patients.