CAJ | 학술논문

目的探讨血浆B型钠尿肽前体水平与急性脑梗死的关系及临床意义. 方法收集2014年3月~2015年5月在我科住院的急性脑梗死患者120例,100例同期年龄相匹配的门诊健康体检者. 所有入选患者于发病24 h内检测B型钠尿肽前体浓度并分为前循环脑梗死组和后循环脑梗死组进行比较. 按梗死面积分为小面积组(<4cm2 )、中度面积组(~10cm2 )、大面积组(>10cm2 )共3个组分别进行比较. 结果急性脑梗死组中患者血浆B型钠尿肽前体水平高于同龄段健康对照组(P<0.05),急性脑梗死梗死面积与血浆B型钠尿肽前体水平呈正相关(P<0.05),急性脑梗死的部位对血浆B型钠尿肽前体水平有一定的影响. 结论血浆B型钠尿肽前体水平对急性脑梗死的诊疗有指导意义.
목적 탐토혈장B형납뇨태전체수평여급성뇌경사적관계급림상의의. 방법 수집2014년3월~2015년5월재아과주원적급성뇌경사환자120례,100례동기년령상필배적문진건강체검자. 소유입선환자우발병24 h내검측B형납뇨태전체농도병분위전순배뇌경사조화후순배뇌경사조진행비교. 안경사면적분위소면적조(<4cm2 )、중도면적조(~10cm2 )、대면적조(>10cm2 )공3개조분별진행비교. 결과 급성뇌경사조중환자혈장B형납뇨태전체수평고우동령단건강대조조(P<0.05),급성뇌경사경사면적여혈장B형납뇨태전체수평정정상관(P<0.05),급성뇌경사적부위대혈장B형납뇨태전체수평유일정적영향. 결론 혈장B형납뇨태전체수평대급성뇌경사적진료유지도의의.
Objective To investigate the Correlattion and clinical significance between plasma B -type brain natriuretic peptide precursor ( proBNP) and acute cerebral infarction .Methods Collected 120 cases of acute cere-bral infarction patients ,admitted to our department from March 2014 to May 2015 and 100 healthy cases in the same pe-riod of age-matched were enrolled in the experiment .All patients were detected the proBNP concentration in the patho-genes of 24 hours and divided into anterior circulation infarction group and posterior circulation infarction group .Accord-ing to the infarct size,all patients were divided into 3 groups:small area group ( <4cm2 ),moderate area group ( ~10cm2),large area group(>10cm2).Results Plasma proBNP levels of acute cerebral infarction group were significant-ly(P<0.05) higher than those of group control .Infarct sizes of acute cerebral infarction and the levels of proBNP were positively correlated(P<0.05),and the location of acute cerebral infarction had a certain influence on proBNP levels . Conclusion The significance of plasma proBNP levels in the diagnosis and treatment of acute cerebral infarction may be instructive .