CAJ | 학술논문

目的:探讨PWI在肝硬化增生性结节(dysplastic nodule,DN)诊断中的应用. 方法:回顾性分析经病理证实的40例DN患者的PWI资料,获得每个DN的时间-信号强度曲线(time intensity curve,TIC)和峰值时间(time to peak,TTP),计算肝脏动脉灌注指数(hepatic perfusion index,HPI). 结果:28例28个DN为低级别DN(low grade DN,LGDN),TIC主要呈缓升缓降型20个,TTP为(41.56±1.67)s,HPI为0.27±0.04;12例14个DN为高级别DN(high grade DN,HGDN),TIC主要呈速升缓降型11个,TTP为(39.81±2.36)s,HPI为0.45±0.06. 结论:PWI能客观地反映DN的血流情况,有助于DN的诊断和鉴别诊断.
목적:탐토PWI재간경화증생성결절(dysplastic nodule,DN)진단중적응용. 방법:회고성분석경병리증실적40례DN환자적PWI자료,획득매개DN적시간-신호강도곡선(time intensity curve,TIC)화봉치시간(time to peak,TTP),계산간장동맥관주지수(hepatic perfusion index,HPI). 결과:28례28개DN위저급별DN(low grade DN,LGDN),TIC주요정완승완강형20개,TTP위(41.56±1.67)s,HPI위0.27±0.04;12례14개DN위고급별DN(high grade DN,HGDN),TIC주요정속승완강형11개,TTP위(39.81±2.36)s,HPI위0.45±0.06. 결론:PWI능객관지반영DN적혈류정황,유조우DN적진단화감별진단.
Objective:To investigate the application of MRI perfusion weighted imaging in diagnosing cirrhotic dysplastic nod-ules (DN). Methods:MRI perfusion weighted imaging of 40 patients with 42 DN proved by pathology were reviewed and ana-lyzed. Time-intensity curve (TIC) of each DN was got. The time to peak (TTP) was recorded and hepatic perfusion index (HPI) was calculated. Results:28 DN of 28 patients were low grade dysplastic nodules (LGDN),their TIC mainly rose slowly and de-creased slowly (20/28,71%). Their TTP and HPI were 41.56±1.67s and 0.27±0.04,respectively. 14 DN of 12 patients were high grade dysplastic nodules (HGDN),their TIC mainly rose quickly and decreased slowly(11/14,79%),TTP and HPI were 39.81± 2.36s and 0.45±0.07,respectively. Conclusions:MRI perfusion weighted imaging could objectively reflect the blood supply in-formation of the DN,and it is helpful in diagnosis and differential diagnosis of DN.