CAJ | 학술논문

目的：探讨隐匿性乳腺癌的临床特点及诊治方案。方法对7例隐匿性乳腺癌患者的临床资料进行回顾性分析。结果7例患者中，5例找到乳腺癌原发灶，并行乳腺癌改良根治术，3例未出现局部复发或远处转移，2例出现远处转移；2例行保乳术患者无局部复发或转移。结论对有腋窝淋巴结转移腺癌无明显原发灶的患者，应高度警惕隐匿性乳腺癌；治疗应采用乳腺癌改良根治术或保乳术及腋窝淋巴结清扫，并行全乳腺及区域淋巴结引流区放疗、化疗、内分泌治疗和可能的靶向治疗。
목적：탐토은닉성유선암적림상특점급진치방안。방법대7례은닉성유선암환자적림상자료진행회고성분석。결과7례환자중，5례조도유선암원발조，병행유선암개량근치술，3례미출현국부복발혹원처전이，2례출현원처전이；2례행보유술환자무국부복발혹전이。결론대유액와림파결전이선암무명현원발조적환자，응고도경척은닉성유선암；치료응채용유선암개량근치술혹보유술급액와림파결청소，병행전유선급구역림파결인류구방료、화료、내분비치료화가능적파향치료。
Objective To investigate the clinical characteristics,diagnosis and treatment of occult breast cancer. Methods The data of 7 patients with occult breast cancer were retrospectively analyzed. Results Primary tumors were detected in 5 of the 7 patients,3 of the 5 patients treated by modified radical mastectomy for breast cancer sur-vived without local recurrence or distant metastases,2 patients occurred distant metastases;2 patients were treated by breast conserving surgery,all survived without diseases. Conclusion Occult breast cancer should be considered in female patients with metastatic adenocarcinoma of the axillary lymph nodes and without obvious primary cancer;treatment of the occult breast cancer could be modified radical mastectomy for breast cancer,breast conserving sur-gery and axillary lymph nodes dissection,followed by radiotherapy to the full-breast and drainage areas of regional lymph nodes ,and chemotherapy ,endocrine therapy and possibly targeted therapy.