CAJ | 학술논문

目的:分析前列腺中央腺体癌3.0 T MRS表现,探讨其诊断价值. 方法:回顾性分析经手术病理证实的11例前列腺中央腺体癌的3.0 T MRI及MRS表现,比较中央腺体癌区及非癌区(胆碱+肌酸)/枸橼酸盐[(Cho+Cre)/Cit]的比值. 结果:MRI检查11例均表现为中央腺体增大;2例中央腺体区信号不均匀,见不规则低信号;8例中央腺体区示低、稍高混杂信号结节;1例中央腺体区弥漫性低、等混杂信号结节,侵入外周带.MRS测得中央腺体癌区(Cho+Cre)/Cit值为2.75±1.34,范围1.12~5.67;非癌区(Cho+Cre)/Cit值为0.65±0.32,范围为0.17~0.98,两者差异有统计学意义(P<0.05). 结论:前列腺中央腺体癌3.0 T MRI信号复杂多样,常规序列不易检出、定性困难;MRS能提供中央腺体癌的代谢信息,有助于提高中央腺体癌的诊断水平.
목적:분석전렬선중앙선체암3.0 T MRS표현,탐토기진단개치. 방법:회고성분석경수술병리증실적11례전렬선중앙선체암적3.0 T MRI급MRS표현,비교중앙선체암구급비암구(담감+기산)/구연산염[(Cho+Cre)/Cit]적비치. 결과:MRI검사11례균표현위중앙선체증대;2례중앙선체구신호불균균,견불규칙저신호;8례중앙선체구시저、초고혼잡신호결절;1례중앙선체구미만성저、등혼잡신호결절,침입외주대.MRS측득중앙선체암구(Cho+Cre)/Cit치위2.75±1.34,범위1.12~5.67;비암구(Cho+Cre)/Cit치위0.65±0.32,범위위0.17~0.98,량자차이유통계학의의(P<0.05). 결론:전렬선중앙선체암3.0 T MRI신호복잡다양,상규서렬불역검출、정성곤난;MRS능제공중앙선체암적대사신식,유조우제고중앙선체암적진단수평.
Objective:To analyze the characteristics of 3.0 T MRS in prostatic central gland cancer and evaluate the value of MRS in diagnosis of prostatic central gland cancer. Methods:3.0 T MRI and MRS findings were reviewed retrospectively in 11 patients with pathologically-confirmed prostatic central gland cancer,and the (choline+creatine)/citrate [(Cho+Cre)/Cit] ratio of the central gland cancer regions and non-cancer regions were compared. Results:Enlargement of central gland was found in MRI of 11 cases. In 2 cases,the signal in central gland was uneven and irregular low signal was found; In 8 cases,low-slight high mixed signal nodular lesions were found;In 1 case,diffuse low-equal mixed signal nodule was found invading peripheral zone. The ratio of (Cho+Cre)/Cit and the range in cancerous and noncancerous regions were 2.75±1.34,1.12~5.67 and 0.65± 0.32,0.17~0.98,respectively. The difference in ratio between the two groups was statistically significant (P<0.05). Conclusion:3.0T MRI signal of prostatic central cancer is complicated. It is not easy to be detected and diagnosed by the routine MRI. MRS can provide the metabolic information of central gland cancer,which is very helpful for the diagnosis of central gland cancer.