CAJ | 학술논문

目的：观察姜黄素治疗黄褐斑的疗效及其对黑素的影响。方法选取2013－05～2014－11间我院皮肤科收治的黄褐斑患者74例，按随机数字表法将其分为观察组和对照组，每组各37例，分别给予姜黄清脂片和维生素C、维生素E口服治疗，观察两组患者临床疗效，并分别于治疗前后采用皮肤多功能测试仪进行黑素指数（ MCI）检测。结果观察组患者治疗痊愈率和总有效率均明显高于对照组（P＜0.05）；治疗后，两组患者MCI均明显降低（P＜0.05），且观察组患者降低幅度明显高于对照组（P＜0.05）。结论姜黄素可有效改善黄褐斑患者皮肤状况，降低MCI。
목적：관찰강황소치료황갈반적료효급기대흑소적영향。방법선취2013－05～2014－11간아원피부과수치적황갈반환자74례，안수궤수자표법장기분위관찰조화대조조，매조각37례，분별급여강황청지편화유생소C、유생소E구복치료，관찰량조환자림상료효，병분별우치료전후채용피부다공능측시의진행흑소지수（ MCI）검측。결과관찰조환자치료전유솔화총유효솔균명현고우대조조（P＜0.05）；치료후，량조환자MCI균명현강저（P＜0.05），차관찰조환자강저폭도명현고우대조조（P＜0.05）。결론강황소가유효개선황갈반환자피부상황，강저MCI。
ObjectiveTodiscussthecurativeeffectofcurcumintreatmentforchloasmaanditseffectonmelanoma.Methods 74pa-tients with melasma were selected and randomly divided into observational group and control group , with 37 cases in each group , and they were treated with curcumin and vitamin C , vitamin E respectively , the clinical effect of the two groups was observed , and the melanin index ( MCI) using skin and multi function test before and after the treatment was detected.Results The cure rate and total effective rate of ob-servation group were significantly higher than those of control group ( P<0.05 ); After treatment , the MCI of the two groups significantly decreased ( P<0.05 ) ,and the changes of observation group were significantly higher than those of control group ( P<0.05 ).Conclusion Curcumin can effectively improve the skin condition , and reduce MCI.