CAJ | 학술논문

目的：探讨经导管肝动脉化疗栓塞术(TACE)联合经皮穿刺微波消融术(MWA)治疗大肝癌的安全性及有效性。方法84例大肝癌患者,随机分为2组,治疗组42例,TACE 术后联合微波消融治疗；对照组42例,对肝内病灶仅行 TACE 治疗。结果治疗组的有效率为71.4%,对照组的有效率为42.8%,2组间的差异有统计学意义(P <0.05)。术后第6、12、18、24个月随访,治疗组的生存率分别为88.1%、73.8%、52.3%、33.3%,对照组的生存率分别为76.2%、57.1%、30.9%、9.5%。2组术后并发症无明显差异。结论TACE 联合 MWA 治疗大肝癌是安全有效的,联合治疗的效果优于单纯行 TACE 治疗。
목적：탐토경도관간동맥화료전새술(TACE)연합경피천자미파소융술(MWA)치료대간암적안전성급유효성。방법84례대간암환자,수궤분위2조,치료조42례,TACE 술후연합미파소융치료；대조조42례,대간내병조부행 TACE 치료。결과치료조적유효솔위71.4%,대조조적유효솔위42.8%,2조간적차이유통계학의의(P <0.05)。술후제6、12、18、24개월수방,치료조적생존솔분별위88.1%、73.8%、52.3%、33.3%,대조조적생존솔분별위76.2%、57.1%、30.9%、9.5%。2조술후병발증무명현차이。결론TACE 연합 MWA 치료대간암시안전유효적,연합치료적효과우우단순행 TACE 치료。
Objective To evaluate the efficacy and safety of transcatheter arterial chemoembolization(TACE)combined with per-cutaneous microwave ablation(MWA)in treatment of large-sized hepatic carcinoma.Methods A total of 84 patients with large-sized hepatic carcinoma were randomly and equally divided into the study group(n=42)and control group(n=42).TACE combined with MWA was carried out in the patients of the study group,while only TACE was performed in the patients of the control group.Results The effective rate of the study group and the control group was 71.4% and 42.8% respectively,and the difference between the two groups was statistically significant(P <0.05).In the study group,the survival rates at 6,12,18,24 months after the treatment were 88.1%,73.8%,52.3% and 33.3% respectively,while in the control group the survival rates were 76.2%,57.1%,30.9% and 9.5%respectively.There was no statistically significant differences in the postoperative complications between the two groups.Conclusion TACE combined with MWA appears to be an effective approach for the treatment of large-sized hepatic carcinoma.The effect of combined therapy is obviously superior to the only TACE.