CAJ | 학술논문

目的：探讨儿童幕上原始神经外胚层肿瘤(PNETs)的 MSCT 和 MRI 表现特征,以提高对此病的认识。方法回顾性分析文献及本院经手术病理证实的6例 PNETs 患者的病例资料。结果发生于左侧颞枕顶叶及额颞叶各1例,右侧额颞叶及颞顶叶各1例,左右侧脑室三角区旁各1例。实性2例,囊性1例,囊实性3例。CT 平扫2例实性呈稍高密度,1例囊性呈低密度,3例囊实性呈高低混杂密度。MRI 平扫5例实性或囊实性 T1 WI 呈与脑灰质等或稍低信号,T2 WI 呈等或稍高信号；1例囊性呈长 T1长 T2信号；DWI 实性呈高信号；3例 MRS 胆碱含量升高,N-乙酰天门冬氨酸、肌酸及脂质下降。增强扫描5例实性或囊实性呈轻~中等强化,1例囊性呈环形强化。结论儿童 PNETs 的影像学表现有一定的特征性,结合发病年龄及病灶部位,有助于与其他颅内肿瘤相鉴别。
목적：탐토인동막상원시신경외배층종류(PNETs)적 MSCT 화 MRI 표현특정,이제고대차병적인식。방법회고성분석문헌급본원경수술병리증실적6례 PNETs 환자적병례자료。결과발생우좌측섭침정협급액섭협각1례,우측액섭협급섭정협각1례,좌우측뇌실삼각구방각1례。실성2례,낭성1례,낭실성3례。CT 평소2례실성정초고밀도,1례낭성정저밀도,3례낭실성정고저혼잡밀도。MRI 평소5례실성혹낭실성 T1 WI 정여뇌회질등혹초저신호,T2 WI 정등혹초고신호；1례낭성정장 T1장 T2신호；DWI 실성정고신호；3례 MRS 담감함량승고,N-을선천문동안산、기산급지질하강。증강소묘5례실성혹낭실성정경~중등강화,1례낭성정배형강화。결론인동 PNETs 적영상학표현유일정적특정성,결합발병년령급병조부위,유조우여기타로내종류상감별。
Objective To explore the imaging features of MSCT and MRI in children with supratentorial primitive neuroectoder-mal tumor (PNETs )in order to improve our understanding of the disease.Methods A retrospective analysis of pathologically proved 6 cases with PNETs patients was performed along with literature review.Results The locations of the 6 PNET lesions in-cluded the left temporal pillow parietal lobe,the frontal temporal lobe each 1 case,right frontal tempora temporal lobe,temporal pa-rietal lobe,left and right lateral ventricle.Among the 6 cases,2 cases showed solid mass,one showed cystic mass,and the other 3 cases showed mixed cystic and solid mass.CT scan showed a slightly higher density in 2 cases with solid mass,low density in one case with cystic mass and mixed high and low density in the other three cases with mixed cystic and solid mass.MRI scan showed iso-or slightly low T1 WI intensity and iso-or high T2 WI intensity of the lesions in five cases with solid or cystic mass.One case with cystic mass showed long T1 and T2 signal.Solid part of the lesion showed high signal on DWI.On MRS,3 cases showed increased choline levels and decreased N-acetyl aspartate creatine and lipid.After contrast enhancement,five cases with solid or cystic mass showed mild to moderate enhancement,one case with cystic mass showed annular enhancement.Conclusion Some imaging features are identified in supratentorial primitive neuroectodermal tumor in children.Combining with the age of onset and the location of the lesion,these imaging features can help differential diagnosis with other intracranial tumors.