医学理论与实践
醫學理論與實踐
의학이론여실천
The Journal of Medical Theory and Practice
2015年
19期
2594-2596
,共3页
TCT%HPV%宫颈癌%临床价值
TCT%HPV%宮頸癌%臨床價值
TCT%HPV%궁경암%림상개치
TCT%HPV%Cervical cancer%Clinical Value
目的:探讨薄层液基细胞学(TCT)结合人乳头瘤病毒(HPV)检测在宫颈癌筛查中的应用价值。方法:选择2013年10月-2015年4月我院妇科门诊973例宫颈异常患者,均行 TCT 和 HPV检测及病理学检查,分析 TCT、HPV检测结果,比较TCT、HPV和TCT+ HPV检测符合率。结果:HPV检测阳性574例(58.99%),CIN Ⅰ、CINⅡ、CIN Ⅲ的 HPV阳性率依次增高。TCT检测不典型鳞状细胞(ASC)以上病变438例(45.02%),其中ASC 108例(24.66%),低度鳞状上皮内病变(LSIL )176例(40.18%),高度鳞状上皮内病变(HSIL )154例(35.16%)。随着CIN病变级别增高,TCT、HPV检测符合率逐步明显增高(P<0.05)。TCT+ HPV检测符合率显著高于TCT、HPV检测(P<0.05)。结论:TCT结合 HPV检测是筛查宫颈癌的有效方法,诊断符合率高于单一检测。
目的:探討薄層液基細胞學(TCT)結閤人乳頭瘤病毒(HPV)檢測在宮頸癌篩查中的應用價值。方法:選擇2013年10月-2015年4月我院婦科門診973例宮頸異常患者,均行 TCT 和 HPV檢測及病理學檢查,分析 TCT、HPV檢測結果,比較TCT、HPV和TCT+ HPV檢測符閤率。結果:HPV檢測暘性574例(58.99%),CIN Ⅰ、CINⅡ、CIN Ⅲ的 HPV暘性率依次增高。TCT檢測不典型鱗狀細胞(ASC)以上病變438例(45.02%),其中ASC 108例(24.66%),低度鱗狀上皮內病變(LSIL )176例(40.18%),高度鱗狀上皮內病變(HSIL )154例(35.16%)。隨著CIN病變級彆增高,TCT、HPV檢測符閤率逐步明顯增高(P<0.05)。TCT+ HPV檢測符閤率顯著高于TCT、HPV檢測(P<0.05)。結論:TCT結閤 HPV檢測是篩查宮頸癌的有效方法,診斷符閤率高于單一檢測。
목적:탐토박층액기세포학(TCT)결합인유두류병독(HPV)검측재궁경암사사중적응용개치。방법:선택2013년10월-2015년4월아원부과문진973례궁경이상환자,균행 TCT 화 HPV검측급병이학검사,분석 TCT、HPV검측결과,비교TCT、HPV화TCT+ HPV검측부합솔。결과:HPV검측양성574례(58.99%),CIN Ⅰ、CINⅡ、CIN Ⅲ적 HPV양성솔의차증고。TCT검측불전형린상세포(ASC)이상병변438례(45.02%),기중ASC 108례(24.66%),저도린상상피내병변(LSIL )176례(40.18%),고도린상상피내병변(HSIL )154례(35.16%)。수착CIN병변급별증고,TCT、HPV검측부합솔축보명현증고(P<0.05)。TCT+ HPV검측부합솔현저고우TCT、HPV검측(P<0.05)。결론:TCT결합 HPV검측시사사궁경암적유효방법,진단부합솔고우단일검측。
Objective :To investigate the application value of TCT combined with HPV detection for cervical cancer screening .Methods :973 cases of abnormal cervical gynecologica in our hospital clinical ,selected from October 2013 to April 2015 ,were performed with TCT and HPV detection and histopathology .The results of TCT ,HPV detection were analyzed ,the compliance rate of TCT ,HPV and TCT+ HPV detection were compared .Results :HPV test positive cases were 574 cases (58 .99% ) ,the HPV‐positive rates of CIN Ⅰ ,CIN Ⅱ ,CIN Ⅲ were gradually increased .The detection of atypical squamous cells (ASC) by TCT were 438 cases of lesions (45 .02% ) ,among them ,there were ASC 108 cases (24 .66% ) ,low‐grade squamous intraepithelial lesions (LSIL)176 cases (40 .18% ) and high‐grade squamous epitheli‐um lesion (HSIL) 154 cases (35 .16% ) .With the increased level of CIN ,the compliance rate of TCT ,HPV were grad‐ually increased significantly (P< 0 .05) .The compliance rate of TCT + HPV detection was significantly higher than that of TCT ,HPV detection(P<0 .05) .Conclusion:TCT combined with HPV detection was an effective method of cer‐vical cancer screening .