CAJ | 학술논문

经皮给药是中药重要的给药途经,其产生疗效的核心环节是使药物的有效成分透过皮肤屏障进入体内.物理促透是中药经皮给药的重要促透方式,是应用物理方法改变皮肤或药物特性,以促进药物透皮吸收的方法.物理促透主要是通过对声、光、电、磁及微针等技术的应用由相应的器械来实现;中药经皮给药产生作用的途径主要通过经皮吸收和经穴(吸收)刺激.通过对经皮给药技术和给药途径的分析,指出中药经皮给药器械发展的方向.
경피급약시중약중요적급약도경,기산생료효적핵심배절시사약물적유효성분투과피부병장진입체내.물리촉투시중약경피급약적중요촉투방식,시응용물리방법개변피부혹약물특성,이촉진약물투피흡수적방법.물리촉투주요시통과대성、광、전、자급미침등기술적응용유상응적기계래실현;중약경피급약산생작용적도경주요통과경피흡수화경혈(흡수)자격.통과대경피급약기술화급약도경적분석,지출중약경피급약기계발전적방향.
Transdermal drug delivery is an important medicine delivery methodology in Chinese medicine, and the core procedure of which is to get the effective components of medicine into the body through the skin barrier successfully.Physical penetration enhancement is an important method to promote the transdermal delivery of Chinese medicine, which by physically changing certain properties of the skin or medicine in order to promote the transdermal absorption.Physical penetration enhancement is mainly via "sound, light, electricity, magnet", and micro needle technology applications by the corresponding equipment.Chinese medicine transdermal technology is mainly through the skin absorption and acupoint stimulating absorption.The focus of this review is trying to predict the development direction of transdermal drug equipment in Chinese medicine by analyzing the transdermal drug delivery technology and pathway.