国际生物医学工程杂志
國際生物醫學工程雜誌
국제생물의학공정잡지
International Journal of Biomedical Engineering
2015年
4期
230-233
,共4页
张静%吴小光%席刚%殷亮%王宏
張靜%吳小光%席剛%慇亮%王宏
장정%오소광%석강%은량%왕굉
低能量激光%脑梗塞%血液流变%高血压
低能量激光%腦梗塞%血液流變%高血壓
저능량격광%뇌경새%혈액류변%고혈압
Low level laser%Cerebral infraction%Hemorheology%Hypertension
目的 探讨低能量激光对脑梗塞合并高血压患者治疗的影响.方法 将脑梗塞合并高血压患者分为传统治疗(对照组)和传统治疗合并激光照射(治疗组)2组,通过在常规药物治疗基础上加用低能激光血管外照射(650 nm,20 mW照射20 min,2次/d,持续2周),评估疗效及观察血液流变学、血压、血脂、神经功能等指标的变化.结果 对照组和治疗组治疗后血液流变指标和血脂均有明显降低,治疗组患者的全血黏度、血浆黏度、全血高切还原黏度、红细胞压积、红细胞变形指数、红细胞刚性指数,纤维蛋白元和血脂下降水平均较对照组显著,差异均具有统计学意义(P＜0.05或P＜0.01).2组治疗后神经缺损功能评分和血压均有明显降低(P＜0.05),治疗组血压下降较对照组明显,差异具有统计学意义(P＜0.05或P＜0.01).结论 650 nm低能量激光的血管外照射在脑梗塞合并高血压患者的治疗中发挥一定的作用,有较好的应用前景.
目的 探討低能量激光對腦梗塞閤併高血壓患者治療的影響.方法 將腦梗塞閤併高血壓患者分為傳統治療(對照組)和傳統治療閤併激光照射(治療組)2組,通過在常規藥物治療基礎上加用低能激光血管外照射(650 nm,20 mW照射20 min,2次/d,持續2週),評估療效及觀察血液流變學、血壓、血脂、神經功能等指標的變化.結果 對照組和治療組治療後血液流變指標和血脂均有明顯降低,治療組患者的全血黏度、血漿黏度、全血高切還原黏度、紅細胞壓積、紅細胞變形指數、紅細胞剛性指數,纖維蛋白元和血脂下降水平均較對照組顯著,差異均具有統計學意義(P＜0.05或P＜0.01).2組治療後神經缺損功能評分和血壓均有明顯降低(P＜0.05),治療組血壓下降較對照組明顯,差異具有統計學意義(P＜0.05或P＜0.01).結論 650 nm低能量激光的血管外照射在腦梗塞閤併高血壓患者的治療中髮揮一定的作用,有較好的應用前景.
목적 탐토저능량격광대뇌경새합병고혈압환자치료적영향.방법 장뇌경새합병고혈압환자분위전통치료(대조조)화전통치료합병격광조사(치료조)2조,통과재상규약물치료기출상가용저능격광혈관외조사(650 nm,20 mW조사20 min,2차/d,지속2주),평고료효급관찰혈액류변학、혈압、혈지、신경공능등지표적변화.결과 대조조화치료조치료후혈액류변지표화혈지균유명현강저,치료조환자적전혈점도、혈장점도、전혈고절환원점도、홍세포압적、홍세포변형지수、홍세포강성지수,섬유단백원화혈지하강수평균교대조조현저,차이균구유통계학의의(P＜0.05혹P＜0.01).2조치료후신경결손공능평분화혈압균유명현강저(P＜0.05),치료조혈압하강교대조조명현,차이구유통계학의의(P＜0.05혹P＜0.01).결론 650 nm저능량격광적혈관외조사재뇌경새합병고혈압환자적치료중발휘일정적작용,유교호적응용전경.
Objective To explore the therapeutic effect of low level laser irradiation (LLLI) on cerebral infraction combined with hypertension.Methods Two groups were divided, conventional treatment group and laser irradiation combined with conventional treatment group.LLLI (650 nm, 20 mW, 20 min, twice a day, two weeks therapy) was used by extravascular way in addition to conventional treatment, while control group employed conventional treatment only.Whole blood viscosity, plasma blood pressure, lipid and neurological function were assessed by comparing the index of the two groups.Results Whole blood viscosity, plasma viscosity, whole blood high shear reductive viscosity, hematokit (HTC), erythrocyte deformation index, erythrocyte rigidity index, fibrinogen and blood lipid level of both groups decreased and the decrease of the testing group was more significant than that of control group (P＜0.05 or P＜0.01).Neurological deficit score an blood pressure of both groups showed significant decrease (P＜0.05), and the decrease in blood pressure of testing group was significant than that of the control group (P＜0.05 or P＜0.01).Conclusions 650 nm extravascular LLLI may be effective in treatment of cerebral infraction combined with hypertension, and has a good application prospect.
