CAJ | 학술논문

目的：统计分析北京市大兴区人民医院近十年乳腺肿物针吸细胞学（FNAC）病例的临床特征及其与手术活检相比诊出恶性肿瘤的敏感度和特异度，为妇女乳腺癌筛查工作的开展提供数据参考。方法回顾整理大兴区医院2005~2014年 FNAC 病例2624例，其中747例进行了手术活检。结果2624例 FNAC 病例中93.6％为女性患者，97.2％位于单侧，83.6％为20~60岁患者；就可疑恶性/恶性肿瘤比例而言，女性远高于男性，单侧高于双侧，年龄长者高于低者。与手术活检对比，FNAC 检出乳腺恶性肿瘤的敏感度是91.3％（285/312），特异度为97.9％（426/435），潜在误诊率为2.1％（9/435），总准确率为95.2％（711/747）。结论应加强对年长女性的乳腺癌筛查力度。与活检诊断比较显示 FNAC 诊断恶性肿瘤的敏感性较高特异性强，提示可将其作为筛查乳腺癌的方法之一。
목적：통계분석북경시대흥구인민의원근십년유선종물침흡세포학（FNAC）병례적림상특정급기여수술활검상비진출악성종류적민감도화특이도，위부녀유선암사사공작적개전제공수거삼고。방법회고정리대흥구의원2005~2014년 FNAC 병례2624례，기중747례진행료수술활검。결과2624례 FNAC 병례중93.6％위녀성환자，97.2％위우단측，83.6％위20~60세환자；취가의악성/악성종류비례이언，녀성원고우남성，단측고우쌍측，년령장자고우저자。여수술활검대비，FNAC 검출유선악성종류적민감도시91.3％（285/312），특이도위97.9％（426/435），잠재오진솔위2.1％（9/435），총준학솔위95.2％（711/747）。결론응가강대년장녀성적유선암사사력도。여활검진단비교현시 FNAC 진단악성종류적민감성교고특이성강，제시가장기작위사사유선암적방법지일。
Objective To provide the data for screening of breast cancer in females with breast mass by analyzing their clinical features of the breast mass and data of fine needle aspiration cytology(FNAC)in the Peopleˊs Hospital of Daxing District in recent 10 years in order to provide the reliability of FNAC examination in diagnosis of breast cancer. Methods The data of 2 624 cases with FNAC examination during 2005 to 2014 were retrospectivelyreviewed,among them 747 cases had underwent biopsies. Results 93. 6% of patients with FNAC examination were females, 97. 2% of them were unilateral breast mass and the age of 83. 6% patients ranged from 20 to 60 years old. The female and senior patients with FNAC examination for unilateral breast mass tended to have a higher proportion of presumed - malignancy or malignant tumors than others. In com-parison with biopsy,the sensitivity,specificity,potential misdiagnostic rate and overall accuracy of FNAC examination in diagnosis of breast cancer were 91. 3%(285 / 312),97. 9%(426 / 435),2. 1%(9 / 435)and 95. 2%(711 / 747)respectively. Conclusion The program for screening of breast cancer should pay more attention on senior women with breast mass. In comparison with the result of biopsy,the sensitivity and specificity of FNAC examination are high,hence it can be used as an importantway for screening of breast cancer.