CAJ | 학술논문

目的：通过回顾分析我科2013年全年救治百草枯中毒病例，分析连二亚硫酸钠还原法尿检百草枯对疗效和预后评估的价值。方法：应用连二亚硫酸钠还原法检测收治的84例百草枯中毒患者尿液百草枯浓度，阳性为血灌指针，阴性者不予灌流。结果：84例百草枯中毒患者经血灌等治疗后90天随访，存活41例（48．8％），死亡43例（51．2％）。存活病例就诊即刻百草枯尿检检测结果明显轻于死亡病例，血灌次数也明显减少。结论：应用连二亚硫酸钠可迅速检测患者尿百草枯浓度，有助于评估患者血药浓度和中毒程度，指导是否给予血灌，尿百草枯持续阳性时间超过72 h，提示预后不良。
목적：통과회고분석아과2013년전년구치백초고중독병례，분석련이아류산납환원법뇨검백초고대료효화예후평고적개치。방법：응용련이아류산납환원법검측수치적84례백초고중독환자뇨액백초고농도，양성위혈관지침，음성자불여관류。결과：84례백초고중독환자경혈관등치료후90천수방，존활41례（48．8％），사망43례（51．2％）。존활병례취진즉각백초고뇨검검측결과명현경우사망병례，혈관차수야명현감소。결론：응용련이아류산납가신속검측환자뇨백초고농도，유조우평고환자혈약농도화중독정도，지도시부급여혈관，뇨백초고지속양성시간초과72 h，제시예후불량。
Objective Through retrospective analysis on the paraquat poisoning cases treated in our section during the whole year of 2013, assess the value that using sodium hydrosulfite reduction method to test paraquat concentration by urinalysis for curative effect and prognosis evaluation. Method:Check the concentration of paraquat in the urine of 84 paraquat poisoning patients who have been received and cured by sodium hydrosulfite reduction method, then take positive as an indicator of hemoperfusion and don’t use hemoperfusion for negative patients. Result:Conducted follow-up visits to the 84 paraquat poisoning patients who have had hemoperfusion and other treatments for 90 days, 41 of them survived (48.8%) and 43 were dead (51.2%). Instant paraquat urinalysis result of the survived patients was obviously less than death cases, and the frequency of hemoperfusion also decreased obviously. Conclusion:By using sodium hydrosulfite, we can rapidly test paraquat concentration in patients' urine which is helpful to assess patients' haemoconcentration and poisoning level, and decide whether to use hemoperfusion or not. If urinalysis of paraquat keeps being positive for more than 72 hours, it can be an indicator of unfavourable prognosis.