CAJ | 학술논문

目的：探讨聚桂醇局部注射治疗婴幼儿颌面部血管瘤的效果。方法：将100例颌面部血管瘤患儿随机分为鱼肝油酸钠加地塞米松组（A组，n＝25）、平阳霉素加地塞米松组（B组，n＝25）、聚桂醇组（C组，n＝25）和聚桂醇加地塞米松组（D组，n＝25），比较各组疗效及不良反应。结果：随访时间2－13个月，A组治愈10例、显效12例、有效1例，2例未能坚持治疗；B组治愈11例、显效10例、有效1例，3例未能坚持治疗；C组治愈18例、显效3例、有效3例，1例未能坚持治疗；D组治愈19例、显效3例、有效2例，1例未能坚持治疗。 C、D组的治愈率明显高于A、B组（P ＜0．05），且C、D组硬化注射后腹部不适和低热的不良反应明显少于 A、B组（P ＜0．05）。结论：以聚桂醇为主的硬化剂局部注射治疗婴幼儿颌面部血管瘤的疗效好，副作用少。
목적：탐토취계순국부주사치료영유인합면부혈관류적효과。방법：장100례합면부혈관류환인수궤분위어간유산납가지새미송조（A조，n＝25）、평양매소가지새미송조（B조，n＝25）、취계순조（C조，n＝25）화취계순가지새미송조（D조，n＝25），비교각조료효급불량반응。결과：수방시간2－13개월，A조치유10례、현효12례、유효1례，2례미능견지치료；B조치유11례、현효10례、유효1례，3례미능견지치료；C조치유18례、현효3례、유효3례，1례미능견지치료；D조치유19례、현효3례、유효2례，1례미능견지치료。 C、D조적치유솔명현고우A、B조（P ＜0．05），차C、D조경화주사후복부불괄화저열적불량반응명현소우 A、B조（P ＜0．05）。결론：이취계순위주적경화제국부주사치료영유인합면부혈관류적료효호，부작용소。
Objective:To explore the effects of lauromacrogol injected locally for infant oral and maxillofacial hemangioma. Methods:100 infants with oral and maxillofacial hemangioma were randomly divided into sodium morrhuate combined with dexamethasone group (group A,n=25), pingyangmycin combined with dexamethasone group (group B,n=25), lauromacrogol group (group C,n=25), and lauromacrogol combined with dexamethasone (group D, n=25). The clinical effects and adverse reactions were compared among the four groups. Results:In group A,10 cases were cured,12 cases markedly effective,1 case effective and 2 cases lost. In group B,11 cases were cured,10 cases markedly effective, 1 case effective and 3 cases lost. In group C,18 cases were cured,3 cases markedly effective,3 case effective and 1 case lost. In group D,19 cases were cured ,3 cases markedly effective, 2 case effective and 1 case lost. The cured rate was significantly higher in group C and group D than that in group A and group B (P <0.05),while the adverse reactions such as abdominal discomfort and low fever were significantly lower in group C and group D than those in group A and group B(P < 0.05). Conclusion: It is effect and less adverse reactions for infant oral and maxillofacial hemangioma treated by lauromacrogol injected locally.