CAJ | 학술논문

目的：探讨利福昔明与双歧杆菌三联活菌胶囊序贯疗法治疗小肠细菌过度生长的效果。方法选择2013年1月-2015年1月在我院就诊的78例小肠细菌过度生长患者作为研究对象，随机分为观察组和对照组各39例，观察组接受14 d利福昔明与14 d 双歧杆菌三联活菌胶囊序贯治疗，对照组仅接受14 d 利福昔明治疗，比较两组疗效。结果观察组与对照组小肠细菌过度生长阳性者转阴率(76.92% vs 53.84%)存在统计学差异(P ＜0.05)；两组临床症状治疗有效率(64.10% vs 53.85%)存在统计学差异(P ＜0.05)。结论利福昔明与双歧杆菌三联活菌胶囊序贯治疗小肠细菌过度生长效果明显。
목적：탐토리복석명여쌍기간균삼련활균효낭서관요법치료소장세균과도생장적효과。방법선택2013년1월-2015년1월재아원취진적78례소장세균과도생장환자작위연구대상，수궤분위관찰조화대조조각39례，관찰조접수14 d리복석명여14 d 쌍기간균삼련활균효낭서관치료，대조조부접수14 d 리복석명치료，비교량조료효。결과관찰조여대조조소장세균과도생장양성자전음솔(76.92% vs 53.84%)존재통계학차이(P ＜0.05)；량조림상증상치료유효솔(64.10% vs 53.85%)존재통계학차이(P ＜0.05)。결론리복석명여쌍기간균삼련활균효낭서관치료소장세균과도생장효과명현。
Objective To investigate the treatment efficacy of rifaximin and bifidobacterium triple viable capsules sequential therapy for small intestinal bacterial overgrowth (SIBO). Methods From January 2013 to January 2015, 78 patients with SIBO in our hospital were chosen as research objects. All patients were randomly divided into observation group (n=39) and control group (n=39), and the observation group received rifaximin and bifidobacterium triple viable capsules sequential therapy for 14 days, while the control group received 14 days of rifaximin alone treatment. After treatment, the differences of curative effect between two groups were compared. Results The differences of turning-negative rate of SIBO between observation group and control group had statistical significance (76.92% vs 53.84%, P < 0.05). There was statistically significant difference of treatment efficiency between observation group and control group (64.10% vs 53.85%, P < 0.05). Conclusion The efficacy of rifaximin and bifidobacterium triple viable capsules sequential therapy for SIBO is obvious.