大家健康(中旬版)
大傢健康(中旬版)
대가건강(중순판)
For All Health
2015年
9期
10-11
,共2页
前S1抗原%乙肝五项指标%肝功能
前S1抗原%乙肝五項指標%肝功能
전S1항원%을간오항지표%간공능
Pre -S1 -Ag%Five indicators of hepatitis B%liver function
目的:探讨前 S1抗原(PreS1Ag)与乙肝五项指标常见模式的相关性及在肝功能评价中的作用。方法:采用 ELISA 检测乙肝患者血清中乙肝五项指标和 PreS1Ag;酶速率法检测血清 ALT 和 AST。结果:PreS1Ag 阳性组中,五项指标模式以"小三阳"所占比例最高,"大三阳"次之,2例为五项全阴性模式。HBsAg(+)PreS1Ag(+)组肝功能指标 ALT、AST 升高率显著高于 HBsAg(+)PreS1Ag(-)组(P <0.05)。结论:PreS1Ag 与乙肝五项指标模式有一定相关性,可以作为 HBV 感染检测的重要补充及乙肝患者肝功能损害的辅助评价指标。
目的:探討前 S1抗原(PreS1Ag)與乙肝五項指標常見模式的相關性及在肝功能評價中的作用。方法:採用 ELISA 檢測乙肝患者血清中乙肝五項指標和 PreS1Ag;酶速率法檢測血清 ALT 和 AST。結果:PreS1Ag 暘性組中,五項指標模式以"小三暘"所佔比例最高,"大三暘"次之,2例為五項全陰性模式。HBsAg(+)PreS1Ag(+)組肝功能指標 ALT、AST 升高率顯著高于 HBsAg(+)PreS1Ag(-)組(P <0.05)。結論:PreS1Ag 與乙肝五項指標模式有一定相關性,可以作為 HBV 感染檢測的重要補充及乙肝患者肝功能損害的輔助評價指標。
목적:탐토전 S1항원(PreS1Ag)여을간오항지표상견모식적상관성급재간공능평개중적작용。방법:채용 ELISA 검측을간환자혈청중을간오항지표화 PreS1Ag;매속솔법검측혈청 ALT 화 AST。결과:PreS1Ag 양성조중,오항지표모식이"소삼양"소점비례최고,"대삼양"차지,2례위오항전음성모식。HBsAg(+)PreS1Ag(+)조간공능지표 ALT、AST 승고솔현저고우 HBsAg(+)PreS1Ag(-)조(P <0.05)。결론:PreS1Ag 여을간오항지표모식유일정상관성,가이작위 HBV 감염검측적중요보충급을간환자간공능손해적보조평개지표。
Objective:To study the relativity between Pre -S1 -Ag and common mode of Five indicators of hepatitis B and the role of Pre -S1 -Ag in the evaluation of liver function.Methods:Pre -S1 -Ag、Five indicators of hepatitis B、ALT、AST were tested by ELISA and Enzyme kinetic method using serum samples of 548 cases as patient group and 205 cases with Pre -S1 -Ag(-)as comparison.Results:The proportions of the common mode of Five indicators of hepatitis B are different in the 548 cases of Pre -S1 -Ag -positive group and 205 cases of Pre -S1 -Ag -negative group,in the Pre -S1 -Ag -positive group, the HBsAg(+)、HBeAb(+)、HBcAb(+)mode share the highest proportion(44.34%),the percentage of HBsAg(+)、HBeAg(+)、HBcAg(+)mode was (34.49%),in the Pre -S1 -Ag -positive group still have the mode that HBsAg、HBsAb、HBeAg、HBeAb、HBcAb were negative (0.55%).Conclusion:HBV Pre -S1 -Ag and the common mode of Five indicators of hepatitis B have some relevance,in practical work,collaborative detection of two ways,comple-ment each other,may more accurately reflect the replication status of HBV infection.The existence of Pre -S1 -Ag is closely related to liver function damage.