CAJ | 학술논문

目的了解口腔黏膜下纤维性变的发病原因,采取相应的应对措施,做好口腔黏膜下纤维性变防治工作.方法采取整群抽样,按Pindborg制定的诊断标准,对湘潭市雨湖区不同类型57个单位的11 046例进行了咀嚼槟榔致口腔黏膜下纤维性变(OSF)的流行病学调查.结果确诊OSF 335例,患病率30.33‰,并存口腔癌4例,口腔癌并存率11.94‰;全部OSF患者均有嚼槟榔史,不嚼槟榔者(含有烟、酒、辣嗜好者)未发现OSF患者;OSF患病率在嚼槟榔嗜好的人群中无性别和年龄差异;OSF患病率与日平均咀嚼槟榔剂量和咀嚼槟榔的年限相关(r=0.28828,P＜0.01);使用不同槟榔添加剂OSF患病率差异有统计学意义;不同嗜好配伍组配对标化检验,7组中有6组患病率差异无统计学意义(P＞0.05),而只吃辣椒的本地人(内对照组1 329例)和外地人(外对照组698例)无OSF患者.结论嚼槟榔是湘潭人患OSF的主要因素,OSF癌患病率低于国外.
목적 료해구강점막하섬유성변적발병원인,채취상응적응대조시,주호구강점막하섬유성변방치공작.방법 채취정군추양,안Pindborg제정적진단표준,대상담시우호구불동류형57개단위적11 046례진행료저작빈랑치구강점막하섬유성변(OSF)적류행병학조사.결과 학진OSF 335례,환병솔30.33‰,병존구강암4례,구강암병존솔11.94‰;전부OSF환자균유작빈랑사,불작빈랑자(함유연、주、랄기호자)미발현OSF환자;OSF환병솔재작빈랑기호적인군중무성별화년령차이;OSF환병솔여일평균저작빈랑제량화저작빈랑적년한상관(r=0.28828,P＜0.01);사용불동빈랑첨가제OSF환병솔차이유통계학의의;불동기호배오조배대표화검험,7조중유6조환병솔차이무통계학의의(P＞0.05),이지흘랄초적본지인(내대조조1 329례)화외지인(외대조조698례)무OSF환자.결론 작빈랑시상담인환OSF적주요인소,OSF암환병솔저우국외.
Objective To understand oral submucous fibrous (OSF) because the hair cause of disease and the quantitative corresponding measures,do a good job in OSF prevention and control work.Methods The quantitative cluster sampling,according to the diagnostic criteria of the development of the Pindborg,yuhu in Xiangtan city of different types of 57 units of 11 046 people to chew areca cause OSF epidemiological investigation.Results OSF 335 diagnosis example,the prevalence rate of 30.33‰,4 cases were oral cancer,oral cancer coexist rate was 11.94‰; All OSF patients had a history of betel nut,no chewing betel nut (containing the cigarette,wine,and spicy aficionados) were not found in patients with OSF; Of OSF prevalence in the chewing hobby was no differences in sex and age in the crowd; OSF prevalence of high and low with length of fixed number of year of average chewing betel nut dose and chewing betel nuts were closely related(r =0.28828,P ＜ 0.01) ; OSF prevalence was different from eating betel nut additive that had a very significant difference.Different hobbies compatibility with standardized test,7 incidence group had 6 group without significant difference,but people only eat chili can (in the control group,1 329) and outsiders no OSF patients (control group,698).Conclusions Survey results confirm that chewing betel nut is the main factor of Xiangtan people of OSF,and OSF carcinoma prevalence is lower than abroad.