首都食品与医药
首都食品與醫藥
수도식품여의약
Capital Medicine
2015年
20期
34-36
,共3页
妊娠糖尿病%孕晚期%血脂%体重变化
妊娠糖尿病%孕晚期%血脂%體重變化
임신당뇨병%잉만기%혈지%체중변화
Diabetes in pregnancy%late pregnancy%blood lipid%body weight change
目的：研究妊娠糖尿病患者妊娠晚期血脂变化及血脂变化与孕前BMI、孕期体重变化的关系。方法选取通过100g葡萄糖口服糖耐量试验筛查,按照美国糖尿病学会标准诊断为妊娠糖尿病的孕晚期妇女156例，记录其孕前、分娩前体重、身高，计算其孕前体质指数、孕期增重，根据孕前体质指数将患者分为消瘦组、正常组、超重组和肥胖组，根据孕期体重增长将患者分为低于正常组、正常组和高于正常组，于孕（29±1）周采空腹静脉血测定TG、TC、HDL-c、LDL-c、Apo A1、Apo B及Lp（a）的值。分析不同孕前BMI、不同孕期增重孕晚期血脂指标之间的差异。结果所有入选患者的孕晚期血脂指标中除Apo B、Lp(a)外，TC、TG、HDL-c、LDL-c、Apo A1的均值均高于正常值范围上限。孕前不同体质指数、孕期不同增重的各组间的血脂指标的水平没有统计学差异。结论 GDM患者孕晚期血脂存在生理性升高，其升高情况与正常妊娠妇女相似，且这种变化与孕前的体质指数及孕期的体重增重无明显相关性。
目的：研究妊娠糖尿病患者妊娠晚期血脂變化及血脂變化與孕前BMI、孕期體重變化的關繫。方法選取通過100g葡萄糖口服糖耐量試驗篩查,按照美國糖尿病學會標準診斷為妊娠糖尿病的孕晚期婦女156例，記錄其孕前、分娩前體重、身高，計算其孕前體質指數、孕期增重，根據孕前體質指數將患者分為消瘦組、正常組、超重組和肥胖組，根據孕期體重增長將患者分為低于正常組、正常組和高于正常組，于孕（29±1）週採空腹靜脈血測定TG、TC、HDL-c、LDL-c、Apo A1、Apo B及Lp（a）的值。分析不同孕前BMI、不同孕期增重孕晚期血脂指標之間的差異。結果所有入選患者的孕晚期血脂指標中除Apo B、Lp(a)外，TC、TG、HDL-c、LDL-c、Apo A1的均值均高于正常值範圍上限。孕前不同體質指數、孕期不同增重的各組間的血脂指標的水平沒有統計學差異。結論 GDM患者孕晚期血脂存在生理性升高，其升高情況與正常妊娠婦女相似，且這種變化與孕前的體質指數及孕期的體重增重無明顯相關性。
목적：연구임신당뇨병환자임신만기혈지변화급혈지변화여잉전BMI、잉기체중변화적관계。방법선취통과100g포도당구복당내량시험사사,안조미국당뇨병학회표준진단위임신당뇨병적잉만기부녀156례，기록기잉전、분면전체중、신고，계산기잉전체질지수、잉기증중，근거잉전체질지수장환자분위소수조、정상조、초중조화비반조，근거잉기체중증장장환자분위저우정상조、정상조화고우정상조，우잉（29±1）주채공복정맥혈측정TG、TC、HDL-c、LDL-c、Apo A1、Apo B급Lp（a）적치。분석불동잉전BMI、불동잉기증중잉만기혈지지표지간적차이。결과소유입선환자적잉만기혈지지표중제Apo B、Lp(a)외，TC、TG、HDL-c、LDL-c、Apo A1적균치균고우정상치범위상한。잉전불동체질지수、잉기불동증중적각조간적혈지지표적수평몰유통계학차이。결론 GDM환자잉만기혈지존재생이성승고，기승고정황여정상임신부녀상사，차저충변화여잉전적체질지수급잉기적체중증중무명현상관성。
Objective To record the blood lipid profile of pregnant women with GDM during late pregnancy, and to study the relationship between maternal lipid levels and the increase in maternal body weight. Methods 156 pregnant women with GDM in late pregnancy, diagnosed by 100g OGTT ADA standard, were included in the present study. TC, TG, HDL-c, LDL-c, Apo A1, Apo B and Lp (a) were determined in their early third - trimester. The height and body weight were measured before delivery. The patients were divided into 4 groups according to their pre- pregnancy body mass index. The body weight gain during pregnancy was the second basis of categorization. Compare the lipid indicators mentioned above between the four BMI groups or between the three body weight gain groups. ResultsTC, TG, HDL-c, LDL - c, Apo A1 -c average were higher than normal range limit, except Apo B and Lp (a). The level of blood lipid index had no statistically difference between each group, no obvious correlation between the changes of blood lipid index and BMI or weight gain.Conclusions In present study, the serum lipid profile in GDM women is similar to that of normal gestation, and the suitability of pre - pregnancy BMI or body weight gain during pregnancy is not related to the serum lipid profile in late pregnancy.
