心血管康复医学杂志
心血管康複醫學雜誌
심혈관강복의학잡지
Chinese Journal of Cardiovascular Rehabilitation Medicine
2015年
5期
561-564
,共4页
心动过速 ,室上性%普罗帕酮%胺碘酮
心動過速 ,室上性%普囉帕酮%胺碘酮
심동과속 ,실상성%보라파동%알전동
Tachycardia,supraventricular%Propafenone%Amiodarone
目的:探讨静脉注射普罗帕酮对阵发性室上性心动过速患者的临床疗效及安全性。方法:选择我院心内科于2009年3月~2014年2月收治的80例阵发性室上性心动过速患者,利用随机数字表法分为普罗帕酮组(静脉给药)和胺碘酮组(静脉给药),各40例。记录两组患者治疗前及治疗后24h的心率、转复窦性心律时间、临床总有效率及不良反应发生率。结果:两组组间总有效率无显著差异( P>0.05)。与胺碘酮组比较,普罗帕酮组复律时间明显缩短[(18.9±3.2) min比(7.3±1.0) min],治疗后24h心率明显降低[(99.6±8.4)次/min比(81.2±5.9)次/min], P均<0.05。结论:静脉注射普罗帕酮与胺碘酮治疗阵发性室上性心动过速的疗效相当,但普罗帕酮复律快,且能显著降低心率,安全性亦佳,值得在临床上推广。
目的:探討靜脈註射普囉帕酮對陣髮性室上性心動過速患者的臨床療效及安全性。方法:選擇我院心內科于2009年3月~2014年2月收治的80例陣髮性室上性心動過速患者,利用隨機數字錶法分為普囉帕酮組(靜脈給藥)和胺碘酮組(靜脈給藥),各40例。記錄兩組患者治療前及治療後24h的心率、轉複竇性心律時間、臨床總有效率及不良反應髮生率。結果:兩組組間總有效率無顯著差異( P>0.05)。與胺碘酮組比較,普囉帕酮組複律時間明顯縮短[(18.9±3.2) min比(7.3±1.0) min],治療後24h心率明顯降低[(99.6±8.4)次/min比(81.2±5.9)次/min], P均<0.05。結論:靜脈註射普囉帕酮與胺碘酮治療陣髮性室上性心動過速的療效相噹,但普囉帕酮複律快,且能顯著降低心率,安全性亦佳,值得在臨床上推廣。
목적:탐토정맥주사보라파동대진발성실상성심동과속환자적림상료효급안전성。방법:선택아원심내과우2009년3월~2014년2월수치적80례진발성실상성심동과속환자,이용수궤수자표법분위보라파동조(정맥급약)화알전동조(정맥급약),각40례。기록량조환자치료전급치료후24h적심솔、전복두성심률시간、림상총유효솔급불량반응발생솔。결과:량조조간총유효솔무현저차이( P>0.05)。여알전동조비교,보라파동조복률시간명현축단[(18.9±3.2) min비(7.3±1.0) min],치료후24h심솔명현강저[(99.6±8.4)차/min비(81.2±5.9)차/min], P균<0.05。결론:정맥주사보라파동여알전동치료진발성실상성심동과속적료효상당,단보라파동복률쾌,차능현저강저심솔,안전성역가,치득재림상상추엄。
Objective:To explore therapeutic effect of intravenous injection of propafenone on patients with paroxys‐mal supraventricular tachycardia (PSVT) and its safety .Methods :A total of 80 PSVT patients ,who were treated in our department of cardiology from Mar 2009 to Feb 2014 ,were selected .According to random number table meth‐od ,they were randomly and equally divided into propafenone group (received propafenone intravenously) and amio‐darone group (received amiodarone intravenously) .Heart rate ,cardioversion time ,clinical total effective rate and incidence rates of adverse reactions were recorded and compared between two groups before and 24h after treat‐ment .Results:There was no significant difference in total effective rate between two groups , P>0.05. Compared with amiodarone group ,there were significant reductions in cardioversion time [ (18.9 ± 3.2) min vs .(7.3 ± 1.0) min] , heart rate after treatment 24 h [ (99.6 ± 8.4) beats/min vs .(81.2 ± 5.9) beats/min] in propafenone group , P<0.05 both .Conclusion:Intravenous injections of propafenone and amiodarone possess similar therapeutic effect on paroxysmal supraventricular tachycardia ,but propafenone can achieve rapid cardioversion and reduce heart rate with satisfying safety ,which is worth further extending .