中华行为医学与脑科学杂志
中華行為醫學與腦科學雜誌
중화행위의학여뇌과학잡지
Chinese Journal of Behavioral Medicine and Brain Science
2015年
9期
838-841
,共4页
酒精%执行功能%抑制%刷新%转换
酒精%執行功能%抑製%刷新%轉換
주정%집행공능%억제%쇄신%전환
Alcohol%Executive function%In(1) bition%Updating%Shifting process
目的 探讨中等剂量的酒精摄入和不同饮酒期望对社会饮酒者执行功能各维度的影响.方法 研究对象为90名大学生,均为社会饮酒者,采用抽签的方式随机分配到饮酒组(31人)、对照组(30人)和安慰剂组(29人).采用Stroop任务、1-Back任务和局部-整体任务分别从抑制、刷新和转换三个方面对执行功能进行测量.结果 饮酒组与对照组相比,在执行功能的抑制[(61.65±26.31) ms,(42.48±32.94)ms]、刷新[(557.23±86.24) ms,(515.02±70.24) ms]和转换[(718.85±246.03) ms,(553.95±151.74) ms]三个维度上的差异均有统计学意义(P＜0.05或P＜0.01);安慰剂组与对照组相比,在执行功能的抑制[(39.25±29.35) ms,(42.48±32.94)ms]、刷新[(516.32±73.25)ms,(515.02±70.24) ms]和转换[(591.20± 193.07) ms,(553.95±151.74) ms]三个维度上的差异均无统计学意义(P＞0.05).饮酒组中,积极期望与执行功能各维度任务的反应时均存在负相关(-0.427,-0.330,-0.383),其中抑制功能和转换功能上的相关系数差异有统计学意义(P＜0.05);消极期望与执行功能各维度任务的反应时均存在正相关(0.251,0.323,0.377),其中转换功能的相关系数差异有统计学意义(P＜0.05).回归分析发现,积极期望对抑制功能和转换功能有显著的负向预测作用.结论 社会饮酒者摄入中等剂量的酒精后执行功能各维度均出现损伤;不同饮酒期望的个体酒后执行功能的损伤有差异.
目的 探討中等劑量的酒精攝入和不同飲酒期望對社會飲酒者執行功能各維度的影響.方法 研究對象為90名大學生,均為社會飲酒者,採用抽籤的方式隨機分配到飲酒組(31人)、對照組(30人)和安慰劑組(29人).採用Stroop任務、1-Back任務和跼部-整體任務分彆從抑製、刷新和轉換三箇方麵對執行功能進行測量.結果 飲酒組與對照組相比,在執行功能的抑製[(61.65±26.31) ms,(42.48±32.94)ms]、刷新[(557.23±86.24) ms,(515.02±70.24) ms]和轉換[(718.85±246.03) ms,(553.95±151.74) ms]三箇維度上的差異均有統計學意義(P＜0.05或P＜0.01);安慰劑組與對照組相比,在執行功能的抑製[(39.25±29.35) ms,(42.48±32.94)ms]、刷新[(516.32±73.25)ms,(515.02±70.24) ms]和轉換[(591.20± 193.07) ms,(553.95±151.74) ms]三箇維度上的差異均無統計學意義(P＞0.05).飲酒組中,積極期望與執行功能各維度任務的反應時均存在負相關(-0.427,-0.330,-0.383),其中抑製功能和轉換功能上的相關繫數差異有統計學意義(P＜0.05);消極期望與執行功能各維度任務的反應時均存在正相關(0.251,0.323,0.377),其中轉換功能的相關繫數差異有統計學意義(P＜0.05).迴歸分析髮現,積極期望對抑製功能和轉換功能有顯著的負嚮預測作用.結論 社會飲酒者攝入中等劑量的酒精後執行功能各維度均齣現損傷;不同飲酒期望的箇體酒後執行功能的損傷有差異.
목적 탐토중등제량적주정섭입화불동음주기망대사회음주자집행공능각유도적영향.방법 연구대상위90명대학생,균위사회음주자,채용추첨적방식수궤분배도음주조(31인)、대조조(30인)화안위제조(29인).채용Stroop임무、1-Back임무화국부-정체임무분별종억제、쇄신화전환삼개방면대집행공능진행측량.결과 음주조여대조조상비,재집행공능적억제[(61.65±26.31) ms,(42.48±32.94)ms]、쇄신[(557.23±86.24) ms,(515.02±70.24) ms]화전환[(718.85±246.03) ms,(553.95±151.74) ms]삼개유도상적차이균유통계학의의(P＜0.05혹P＜0.01);안위제조여대조조상비,재집행공능적억제[(39.25±29.35) ms,(42.48±32.94)ms]、쇄신[(516.32±73.25)ms,(515.02±70.24) ms]화전환[(591.20± 193.07) ms,(553.95±151.74) ms]삼개유도상적차이균무통계학의의(P＞0.05).음주조중,적겁기망여집행공능각유도임무적반응시균존재부상관(-0.427,-0.330,-0.383),기중억제공능화전환공능상적상관계수차이유통계학의의(P＜0.05);소겁기망여집행공능각유도임무적반응시균존재정상관(0.251,0.323,0.377),기중전환공능적상관계수차이유통계학의의(P＜0.05).회귀분석발현,적겁기망대억제공능화전환공능유현저적부향예측작용.결론 사회음주자섭입중등제량적주정후집행공능각유도균출현손상;불동음주기망적개체주후집행공능적손상유차이.
Objective To explore the influence on each dimension of executive function of social drinkers with moderate dose of alcohol intake and different alcohol expectations.Methods 90 university students who were social drinkers allocated randomly by a lottery method to drinking group (n=31),control group (n=30) and placebo group (n=29).The Stroop task,1-Back task and local-global task were employed to measure executive function from three aspects respectively,namely the inhibition,updating and shifting process.Results Drinking group was compared with the Control group in the three dimensions of executive function:inhibition ((61.65 ± 26.31) ms,(42.48 ± 32.94) ms),updating ((557.23 ± 86.24) ms,(515.02 ± 70.24) ms),and shifting process ((718.85±246.03) ms,(553.95± 151.74) ms).The differences were statistically significant (P＜0.05 or P＜0.01).Placebo group was compared with the control group,in the three dimensions of executive function:inhibition ((39.25±29.35) ms,(42.48±32.94) ms),updating ((516.32±73.25) ms,(515.02±70.24) ms),and shifting process ((591.20± 193.07) ms,(553.95± 151.74) ms),all the differences had no statistically significance (P＞ 0.05).In the drinking group,positive expectation was negatively related to each dimension of executive function (-0.427,-0.330,-0.383).The inhibition and the shifting process appeared significant correlation(P＜0.05).Negative expectation was positively related to each dimension of executive function (0.251,0.323,0.377).The shifting process appeared significant correlation (P＜0.05).Regression analysis showed that positive expectation was significantly negative predictions of inhibition and shifting process.Conclusion Executive function of social drinkers is damaged after moderate alcohol intake,and there are differences between executive function damage of different alcohol expectancy drinkers.
