CAJ | 학술논문

目的探讨微创外科联合前哨淋巴结活检术治疗早期胃癌的可行性及临床疗效.方法对2008年12月至2014年1月在江南大学附属医院行微创外科联合前哨淋巴结活检术治疗早期胃癌39例患者的临床资料进行回顾性分析.结果本组39例早期胃癌患者中36例行前哨淋巴结活检+内镜下黏膜剥离术,3例行前哨淋巴结活检+腹腔镜远端胃癌D2根治术.前哨淋巴结平均(2.8±1.0)枚,前哨淋巴结检出率为100％,阳性率为8％,淋巴结状态评估准确率为100％,无假阴性.内镜下黏膜剥离术组有2例患者分别出现局部复发和肝转移,腹腔镜组有1例患者出现肝、肺转移.本组总无病生存率为95％.结论微创外科联合前哨淋巴结活检术治疗早期胃癌是安全、有效的,在根治肿瘤的前提下最大限度地改善了患者术后生存质量.
목적 탐토미창외과연합전초림파결활검술치료조기위암적가행성급림상료효.방법 대2008년12월지2014년1월재강남대학부속의원행미창외과연합전초림파결활검술치료조기위암39례환자적림상자료진행회고성분석.결과 본조39례조기위암환자중36례행전초림파결활검+내경하점막박리술,3례행전초림파결활검+복강경원단위암D2근치술.전초림파결평균(2.8±1.0)매,전초림파결검출솔위100％,양성솔위8％,림파결상태평고준학솔위100％,무가음성.내경하점막박리술조유2례환자분별출현국부복발화간전이,복강경조유1례환자출현간、폐전이.본조총무병생존솔위95％.결론 미창외과연합전초림파결활검술치료조기위암시안전、유효적,재근치종류적전제하최대한도지개선료환자술후생존질량.
Objective To evaluate the feasibility and clinical efficacy of minimally invasive surgery combined with sentinel lymph node (SLN) biopsy for early gastric cancer (EGC).Methods The clinical data of 39 EGC patients undergoing minimally invasive surgery combined with sentinel lymph node biopsy from December 2008 to January 2014 were analyzed retrospectively.Results 36 SLN negative EGC patients received endoscopic submucosal dissection (ESD), and 3 SLN positive EGC patients underwent laparoscopic distal gastrectomy with D2 dissection.The mean number of SLN was (2.8 ± 1.0).The SLN detection rate and accuracy of determination of lymph node (LN) status were both 100％.The rate of LN metastasis in patients with EGC was 8％ with no false negative rate.In ESD group, local recurrence and liver metastasis developed in one each cases.Meanwhile 1 patient in laparoscopic group sufferd postoperative liver and lung metastasis.Total disease free survival was 95％.Conclusions Minimally invasive surgery combined with sentinel lymph node biopsy for EGC is both safe and feasible.