CAJ | 학술논문

目的：评价纳米碳混悬液在甲状腺乳头状癌中央区淋巴结清扫中的疗效。方法72例甲状腺癌患者采用随机数字表法随机分为2组：示踪组36例，对照组36例。示踪组在术中注射纳米碳，据淋巴结显色情况进行淋巴结清扫，对照组直接进行淋巴结清扫。比较2组清扫淋巴结数量、淋巴结转移程度及术后发生甲状旁腺功能低下的情况。结果示踪组的淋巴结检获数312枚，明显高于对照组189枚（P＜0.01，t＝8.476）；术后示踪组发生甲状旁腺功能低下1例，明显少于对照组8例（ P＜0.05，χ2＝4.571）；术后检出淋巴结转移情况无统计学差异（ P＞0.01，χ2＝1.048）。结论甲状腺乳头状癌中央区淋巴结清扫采用淋巴结示踪技术可提高中央区淋巴结清除数量，减少甲状旁腺功能减退情况的发生，提高手术效果。
목적：평개납미탄혼현액재갑상선유두상암중앙구림파결청소중적료효。방법72례갑상선암환자채용수궤수자표법수궤분위2조：시종조36례，대조조36례。시종조재술중주사납미탄，거림파결현색정황진행림파결청소，대조조직접진행림파결청소。비교2조청소림파결수량、림파결전이정도급술후발생갑상방선공능저하적정황。결과시종조적림파결검획수312매，명현고우대조조189매（P＜0.01，t＝8.476）；술후시종조발생갑상방선공능저하1례，명현소우대조조8례（ P＜0.05，χ2＝4.571）；술후검출림파결전이정황무통계학차이（ P＞0.01，χ2＝1.048）。결론갑상선유두상암중앙구림파결청소채용림파결시종기술가제고중앙구림파결청제수량，감소갑상방선공능감퇴정황적발생，제고수술효과。
Objective To evaluate the curative effects of carbon nanoparticles on central lymphnode dis -section in papillary thyroid carcinoma ( PTC) .Methods 72 PTC patients were randomly divided into two groups:carbon nanoparticle group(n=32)and the control group(n=32).Patients in the carbon nanoparticle group were injected with carbon nanoparticles during surgery .Patients in the control group had conventional surgery .The number of lymph nodes being dissected ,lymph node metastasis , and the rate of hypoparathyroidism were compared between the two groups .Results The number of lymph nodes dissected in nanoparticle group ( n =312 ) was much bigger than that in the control group (n=189)(P<0.01;t=8.476).The incidence of hypoparathyroidism in nanoparticle group(n=1)was much lower than that in the control group (n=8)(P<0.05;χ2 =4.571).The metastasis of lymph nodes has no significant difference between the two groups (P>0.01;χ2 =1.048).Conclu-sions The lymphatic tracer technique may improve the number of lymph nodes dissected in central region of PTC and reduce parathyroid gland damage .