CAJ | 학술논문

目的：对新疆喀什地区维吾尔族人群进行干眼症调查和分析，了解西部高原沙漠地区干眼的患病率及危险因素。方法横断面调查研究。于2013年1-12月间，对新疆喀什地区3个街道的常住维吾尔族人群进行干眼调查，所有受检者均进行问卷调查，并予以裂隙灯显微镜、荧光素染色、泪膜破裂时间（BUT）、泪液分泌试验（Schirmer Ⅰ test，SⅠT）等检查。采用卡方检验、logistic回归及方差分析对数据进行分析。结果在接受调查的829例维吾尔族人中，诊断为干眼者180例，占21.7%。其中男性干眼患病率为19.1%（45/235），女性为22.7%（135/594），性别差异无统计学意义；不同年龄组之间干眼的患病率差异有统计学意义（χ2=19.20，P<0.05）；>60岁组干眼患病率[29.0%（62/214）]，高于<60岁组[19.2%（118/615）]（χ2=8.94，P<0.05）。且>60岁组人群中，女性的干眼症患病率比男性高（χ2=6.49， P<0.05）。性别、年龄、糖尿病、高血压是干眼相关的危险因素。SⅠT、BUT等随年龄增长呈下降趋势。结论喀什地区维吾尔族人群中，男女干眼患病率无明显差异。随年龄增大干眼的患病率升高。全身并发疾病对干眼的发生也存在一定影响。
목적：대신강객십지구유오이족인군진행간안증조사화분석，료해서부고원사막지구간안적환병솔급위험인소。방법횡단면조사연구。우2013년1-12월간，대신강객십지구3개가도적상주유오이족인군진행간안조사，소유수검자균진행문권조사，병여이렬극등현미경、형광소염색、루막파렬시간（BUT）、루액분비시험（Schirmer Ⅰ test，SⅠT）등검사。채용잡방검험、logistic회귀급방차분석대수거진행분석。결과재접수조사적829례유오이족인중，진단위간안자180례，점21.7%。기중남성간안환병솔위19.1%（45/235），녀성위22.7%（135/594），성별차이무통계학의의；불동년령조지간간안적환병솔차이유통계학의의（χ2=19.20，P<0.05）；>60세조간안환병솔[29.0%（62/214）]，고우<60세조[19.2%（118/615）]（χ2=8.94，P<0.05）。차>60세조인군중，녀성적간안증환병솔비남성고（χ2=6.49， P<0.05）。성별、년령、당뇨병、고혈압시간안상관적위험인소。SⅠT、BUT등수년령증장정하강추세。결론객십지구유오이족인군중，남녀간안환병솔무명현차이。수년령증대간안적환병솔승고。전신병발질병대간안적발생야존재일정영향。
Objective To describe the prevalence of dry eye in a population of Uighurs in Kashi, Xinjiang, and to analyze the risk factors and characteristics of dry eye. Methods This was a cross-sectional study. Uighurs in the Kashi area of Xinjiang Province were invited to participate in the study from January 2013 to December 2013. An oral consent was obtained from each participant. Every study subject completed a dry eye questionnaire. Slit-lamp microscopy examination , fluorescein staining of the cornea (FL), tear-film break-up time (BUT) and a Schirmer Ⅰ test (SⅠT) were performed to evaluate the clinical manifestations of the disease. Chi-square test and logistic regression were performed to evaluate the differences between various groups. Results In this population of Uighurs, 21.7% (180/829) were diagnosed with dry eye. The prevalence of dry eye in males was 19.1% (45/235) and 22.7% in females (135/594). The difference between genders was not significance. The prevalence of dry eye in people over 60 years of age was higher than in people under 60 years (χ2=8.94, P<0.05). The prevalence of dry eye was higher in females than in males in people over 60 years of age (χ2=6.49, P<0.05). The relative risk factors for dry eye were gender, age, diabetes, and hypertension. Conclusion The prevalence of dry eye among Uighurs in Kashi was different from people who live in the eastern plains area of China. The prevalence of dry eye increases as people become older. The relative risk factors for dry eye were gender, become older, diabetes, and hypertension.