中国继续医学教育
中國繼續醫學教育
중국계속의학교육
China Continuing Medical Education
2015年
29期
192-193
,共2页
阿托伐他汀%短暂性脑缺血发作
阿託伐他汀%短暫性腦缺血髮作
아탁벌타정%단잠성뇌결혈발작
Atorvastatin%Transient ischemic attack
目的探讨阿托伐他汀对短暂性脑缺血发作（TIA）患者转归的影响。方法选择我院神经内科120例TIA患者，随机分为观察组（40 mg/d）和对照组（10 mg/d），各60例，两组患者给予相同的基础治疗，观察两组患者住院及随诊1年内TIA复发及形成梗死、新发冠脉事件、脑出血及死亡情况，比较两组患者1年时LDL水平。结果住院和随访期间，观察组TIA复发率、梗死、新发冠脉事件发生率及LDL水平低于对照组，P＜0.05，差异具有统计学意义。结论高剂量（40 mg/d）阿托伐他汀能改善短暂性脑缺血患者的发作次数。
目的探討阿託伐他汀對短暫性腦缺血髮作（TIA）患者轉歸的影響。方法選擇我院神經內科120例TIA患者，隨機分為觀察組（40 mg/d）和對照組（10 mg/d），各60例，兩組患者給予相同的基礎治療，觀察兩組患者住院及隨診1年內TIA複髮及形成梗死、新髮冠脈事件、腦齣血及死亡情況，比較兩組患者1年時LDL水平。結果住院和隨訪期間，觀察組TIA複髮率、梗死、新髮冠脈事件髮生率及LDL水平低于對照組，P＜0.05，差異具有統計學意義。結論高劑量（40 mg/d）阿託伐他汀能改善短暫性腦缺血患者的髮作次數。
목적탐토아탁벌타정대단잠성뇌결혈발작（TIA）환자전귀적영향。방법선택아원신경내과120례TIA환자，수궤분위관찰조（40 mg/d）화대조조（10 mg/d），각60례，량조환자급여상동적기출치료，관찰량조환자주원급수진1년내TIA복발급형성경사、신발관맥사건、뇌출혈급사망정황，비교량조환자1년시LDL수평。결과주원화수방기간，관찰조TIA복발솔、경사、신발관맥사건발생솔급LDL수평저우대조조，P＜0.05，차이구유통계학의의。결론고제량（40 mg/d）아탁벌타정능개선단잠성뇌결혈환자적발작차수。
Objective To explore the effect of atorvastatin on patients with transient ischemic attack (TIA).Methods 120 patients with TIA (Transient Ischemia Attach, TIA) were randomly divided into observation group (40 mg/d) and control group (10 mg/d) in the internal medicine-neurology of our hospital. Two groups were treated with the same basic treatment. The recurrence of TIA, the formation of infarction, new coronary events, the incidence of cerebral hemorrhage and death, were observed during hospitalization and follow up one year in the two groups. LDL level of two groups was compared at one year after discharge.Results The TIA recurrence rate, cerebral infarction and less new coronary events and LDL level of observation group were lower than the control group,P<0.05, had difference statistically significance.Conclusion The high dose of atorvastatin (40 mg/d) can signiifcantly improve the attack of patients with transient cerebral ischemia.
