中国继续医学教育
中國繼續醫學教育
중국계속의학교육
China Continuing Medical Education
2015年
29期
154-156
,共3页
替吉奥%三维适型放疗%直肠癌
替吉奧%三維適型放療%直腸癌
체길오%삼유괄형방료%직장암
Tegafur%Three-dimensional conformal radiotherapy%Rectal cancer
目的：研究替吉奥同步三维适形放疗治疗老年直肠癌的临床疗效。方法抽取2013年2月～2014年5月我院收治的老年结肠癌患者98例，按照随机数字表法分为对照组和观察组，各49例。均进行三维适形放疗，观察组加用替吉奥早晚口服化疗，治疗2个月后观察对比两组患者治疗疗效及不良反应情况。结果观察组治疗结束后有效率79.6%高于对照组51.0%，P＜0.05，差异具有统计学意义；观察组治疗后胃肠道反应发生率65.3%，高于对照组42.9%，P＜0.05，差异具有统计学意义；观察组骨髓抑制发生率63.3%，对照组42.9%，P＜0.05，差异具有统计学意义；观察组放射性食管炎发生率为53.1%，对照组51.0%，P＞0.05，差异不具有统计学意义。结论替吉奥同步三维适形放疗治疗老年直肠癌疗效好，安全性高。
目的：研究替吉奧同步三維適形放療治療老年直腸癌的臨床療效。方法抽取2013年2月～2014年5月我院收治的老年結腸癌患者98例，按照隨機數字錶法分為對照組和觀察組，各49例。均進行三維適形放療，觀察組加用替吉奧早晚口服化療，治療2箇月後觀察對比兩組患者治療療效及不良反應情況。結果觀察組治療結束後有效率79.6%高于對照組51.0%，P＜0.05，差異具有統計學意義；觀察組治療後胃腸道反應髮生率65.3%，高于對照組42.9%，P＜0.05，差異具有統計學意義；觀察組骨髓抑製髮生率63.3%，對照組42.9%，P＜0.05，差異具有統計學意義；觀察組放射性食管炎髮生率為53.1%，對照組51.0%，P＞0.05，差異不具有統計學意義。結論替吉奧同步三維適形放療治療老年直腸癌療效好，安全性高。
목적：연구체길오동보삼유괄형방료치료노년직장암적림상료효。방법추취2013년2월～2014년5월아원수치적노년결장암환자98례，안조수궤수자표법분위대조조화관찰조，각49례。균진행삼유괄형방료，관찰조가용체길오조만구복화료，치료2개월후관찰대비량조환자치료료효급불량반응정황。결과관찰조치료결속후유효솔79.6%고우대조조51.0%，P＜0.05，차이구유통계학의의；관찰조치료후위장도반응발생솔65.3%，고우대조조42.9%，P＜0.05，차이구유통계학의의；관찰조골수억제발생솔63.3%，대조조42.9%，P＜0.05，차이구유통계학의의；관찰조방사성식관염발생솔위53.1%，대조조51.0%，P＞0.05，차이불구유통계학의의。결론체길오동보삼유괄형방료치료노년직장암료효호，안전성고。
Objective To study the clinical effect of tegafur synchronous three-dimensional conformal radiotherapy in treating elderly patients with rectal cancer.MethodsSelected 98 cases of elderly patients with rectal cancer from February 2013 to May 2014 in our hospital, were divided into the control group and the observation group, each group had 49 cases, according to the random number table method, all the patients received three dimensional conformal radiotherapy and the observation group were additionally treated with tegafur in the morning and at night for oral chemotherapy. After 2 months of treatment, the treatment effect and adverse reactions of the two groups were observed and compared.Results In the observation group, the efifciency after the end of the treatment was 79.6% higher than 51.0% of the control group ,P<0.05, had difference statistically significance, After the treatment, the incidence rate of gastrointestinal reactions in the observation group was 65.3% higher than 42.9% of the control group ,P<0.05, had difference statistically significance, the incidence rate of myelosuppression in the observation group was 63.3% while the control group was 42.9% ,P<0.05, had difference statistically signiifcance, The incidence rate of radiation esophagitis in the observation group was 53.1% and compared with 51.0% in the control group,P>0.05, had no difference statistically signiifcance.Conclusion The curative effect of tegafur synchronous three-dimensional conformal radiotherapy in treating elderly patients with rectal cancer is good, with high safety.
