CAJ | 학술논문

目的：采用单心动周期实时三维超声心动图(sRT-3DE)测量健康成人右室容积和射血分数，探讨其正常参考值范围及变化规律。方法选取334例健康成人，按性别分为男性组和女性组，按年龄分为6个组。应用 sRT-3DE 测量不同性别及年龄组健康成人右室容积和射血分数，对右室容积参数用体表面积(BSA)和瘦体重(LBM)标化，统计分析得到上述参数正常值范围，并研究其在性别间的差异以及与体型特征(身高、体质量、体质指数、BSA、LBM)的相关性。结果348例健康成人中334例(96%)完成sRT-3DE 检查，标化前男性组右室舒张末容积(RVEDV)、右室收缩末容积(RVESV)、右室每搏输出量(RVSV)大于女性组，差异具有统计学意义(P <0.001)，两组间右室射血分数(RVEF)差异无统计学意义(P >0.05)；LBM 标化后男性组 RVEDV、RVESV、RVSV 小于女性组，差异具有统计学意义(P <0.001)；不同年龄组 RVEDV、RVESV、RVSV 差异具有统计学意义(P <0.05)，而 RVEF 差异无统计学意义(P >0.05)；RVEDV、RVESV、RVSV 均与身高、体质量、体质指数、BSA 及 LBM 呈正相关，与年龄呈负相关；RVEF 与以上因素均无相关性。结论本研究采用 sRT-3DE 初步提供了不同性别及年龄组健康成人右室容积和射血分数的正常参考范围，并发现 LBM 在成人心脏结构中有一定影响，为临床右心疾病的诊疗提供有价值的依据。
목적：채용단심동주기실시삼유초성심동도(sRT-3DE)측량건강성인우실용적화사혈분수，탐토기정상삼고치범위급변화규률。방법선취334례건강성인，안성별분위남성조화녀성조，안년령분위6개조。응용 sRT-3DE 측량불동성별급년령조건강성인우실용적화사혈분수，대우실용적삼수용체표면적(BSA)화수체중(LBM)표화，통계분석득도상술삼수정상치범위，병연구기재성별간적차이이급여체형특정(신고、체질량、체질지수、BSA、LBM)적상관성。결과348례건강성인중334례(96%)완성sRT-3DE 검사，표화전남성조우실서장말용적(RVEDV)、우실수축말용적(RVESV)、우실매박수출량(RVSV)대우녀성조，차이구유통계학의의(P <0.001)，량조간우실사혈분수(RVEF)차이무통계학의의(P >0.05)；LBM 표화후남성조 RVEDV、RVESV、RVSV 소우녀성조，차이구유통계학의의(P <0.001)；불동년령조 RVEDV、RVESV、RVSV 차이구유통계학의의(P <0.05)，이 RVEF 차이무통계학의의(P >0.05)；RVEDV、RVESV、RVSV 균여신고、체질량、체질지수、BSA 급 LBM 정정상관，여년령정부상관；RVEF 여이상인소균무상관성。결론본연구채용 sRT-3DE 초보제공료불동성별급년령조건강성인우실용적화사혈분수적정상삼고범위，병발현 LBM 재성인심장결구중유일정영향，위림상우심질병적진료제공유개치적의거。
Objective To analyze the normal reference values of the right ventricular volumes and ejection fraction of healthy adults measured by single-beat real-time three-dimensional echocardiography (sRT-3DE).Methods The subjects of this study included three hundred and thirty-four healthy adults,and were divided into 2 groups by gender and 6 groups by age.The sRT-3DE was chosen to measure their right ventricular volumes and ejection fraction.The parameters of right ventricular volumes were standardized by body surface area (BSA)and lean body mass (LBM)to calculate the ranges of their normal value.The correlation between these parameters and genders as well as the physical characteristics (height,weight, body mass index,BSA and LBM)was also clarified.Results Three hundred and thirty-four (96%)of the 348 subjects had been tested.Before standardizing,men had larger right ventricular volumes compared with women,and the differences of the right ventricular end diastolic volume (RVEDV),right ventricular end systolic volume (RVESV)and right ventricle stroke volume (RVSV)were statistically significant(P <0.001 ),but it had no statistical significance in the difference of the right ventricular ejection fraction (RVEF)(P >0.05 ).After standardizing by LBM,the RVEDV,RVESV and RVSV in male group were significantly lower than those in women group (P < 0.001 ).In different age groups,the difference of RVEDV,RVESV,RVSV ,but no RVEF were statistically significant (P < 0.05 ).Positive correlations between the RVEDV,RVESV,RVSV and the BSA,height,weight,body mass index and LBM had been detected,and it showed a negative relation between RVEDV,RVESV,RVSV with age.Noticeably,RVEF had no correlation with them.Conclusions sRT-3DE can provide a preliminary range for normal reference values of right ventricular volumes and RVEF in healthy adults according to gender and age and finds that LBM has certain impact on adult cardiac structure,which offers valuable evidence for the diagnosis of right heart diseases in clinical practices.