解放军医学院学报
解放軍醫學院學報
해방군의학원학보
Academic Journal of Chinese Pla Medical School
2015年
11期
1118-1121
,共4页
维生素A%维生素E%妊娠
維生素A%維生素E%妊娠
유생소A%유생소E%임신
vitamin A%vitamin E%pregnancy
目的：分析妊娠早、中、晚期血清维生素A、E水平，评价妊娠期维生素的营养状况，指导孕妇妊娠期合理补充维生素。方法收集2013年1月-2014年6月北京地区孕妇妊娠早、中、晚期血清样本共28023份，采用高效液相色谱法定量测定血清维生素A、E的浓度，并与正常人群血清维生素A、E的浓度作比较。结果孕妇妊娠早、中、晚期血清维生素A检测值分别为(0.33±0.08) mg/L、(0.37±0.09) mg/L、(0.33±0.15) mg/L，总体异常率25.31%，以缺乏为主要表现(24.98%)，缺乏率在妊娠早期(38.23%)大于妊娠晚期(35.1%)；孕妇妊娠早、中、晚期血清维生素E检测值分别为(9.10±2.47) mg/L、(14.24±3.66) mg/L、(15.80±5.01) mg/L，总体异常率5.60%，以过量为主要表现(5.37%)，妊娠早期异常率最低(1.26%)，缺乏率(0.76%)与过量率(0.5%)相当，随着孕周增加，维生素E异常率也逐渐增加，妊娠晚期达到最高(15.32%)，均为维生素E过量。结论妊娠各期血清维生素A、E水平不同，维生素A以缺乏为主，维生素E以过量为主，因此重视孕期维生素A、E水平监测，合理正确补充，对保障母婴安全有重要意义。
目的：分析妊娠早、中、晚期血清維生素A、E水平，評價妊娠期維生素的營養狀況，指導孕婦妊娠期閤理補充維生素。方法收集2013年1月-2014年6月北京地區孕婦妊娠早、中、晚期血清樣本共28023份，採用高效液相色譜法定量測定血清維生素A、E的濃度，併與正常人群血清維生素A、E的濃度作比較。結果孕婦妊娠早、中、晚期血清維生素A檢測值分彆為(0.33±0.08) mg/L、(0.37±0.09) mg/L、(0.33±0.15) mg/L，總體異常率25.31%，以缺乏為主要錶現(24.98%)，缺乏率在妊娠早期(38.23%)大于妊娠晚期(35.1%)；孕婦妊娠早、中、晚期血清維生素E檢測值分彆為(9.10±2.47) mg/L、(14.24±3.66) mg/L、(15.80±5.01) mg/L，總體異常率5.60%，以過量為主要錶現(5.37%)，妊娠早期異常率最低(1.26%)，缺乏率(0.76%)與過量率(0.5%)相噹，隨著孕週增加，維生素E異常率也逐漸增加，妊娠晚期達到最高(15.32%)，均為維生素E過量。結論妊娠各期血清維生素A、E水平不同，維生素A以缺乏為主，維生素E以過量為主，因此重視孕期維生素A、E水平鑑測，閤理正確補充，對保障母嬰安全有重要意義。
목적：분석임신조、중、만기혈청유생소A、E수평，평개임신기유생소적영양상황，지도잉부임신기합리보충유생소。방법수집2013년1월-2014년6월북경지구잉부임신조、중、만기혈청양본공28023빈，채용고효액상색보법정량측정혈청유생소A、E적농도，병여정상인군혈청유생소A、E적농도작비교。결과잉부임신조、중、만기혈청유생소A검측치분별위(0.33±0.08) mg/L、(0.37±0.09) mg/L、(0.33±0.15) mg/L，총체이상솔25.31%，이결핍위주요표현(24.98%)，결핍솔재임신조기(38.23%)대우임신만기(35.1%)；잉부임신조、중、만기혈청유생소E검측치분별위(9.10±2.47) mg/L、(14.24±3.66) mg/L、(15.80±5.01) mg/L，총체이상솔5.60%，이과량위주요표현(5.37%)，임신조기이상솔최저(1.26%)，결핍솔(0.76%)여과량솔(0.5%)상당，수착잉주증가，유생소E이상솔야축점증가，임신만기체도최고(15.32%)，균위유생소E과량。결론임신각기혈청유생소A、E수평불동，유생소A이결핍위주，유생소E이과량위주，인차중시잉기유생소A、E수평감측，합리정학보충，대보장모영안전유중요의의。
Objective To study and analyze serum levels of vitamin A, E in early, middle and late pregnancy, evaluate vitamin nutritional status in pregnancy and provide guidance for pregnant women about vitamin supplements during pregnancy.Methods A total of 28 023 serum samples from pregnant women during early, middle and late pregnancy from January 2013 to June 2014 in Beijing were collected, then high performance liquid chromatography (HPLC) method was used to determine the concentration of serum vitamin A and E, and it was compared with serum concentrations of vitamin A, E in normal people.ResultsIn early, middle and late pregnancy, the serum concentration of vitamin A was (0.33±0.08) mg/L, (0.37±0.09) mg/L, (0.33±0.15) mg/L, respectively. The total abnormal rate was 25.31% with main performance of lacking (24.98%). The rate of lacking in thefirst trimester of pregnancy (38.23%) was higher than late pregnancy (35.1%). The serum concentration of vitamin E was (9.10±2.47) mg/L, (14.24±3.66) mg/L, (15.80±5.01) mg/L, respectively. The total abnormal rate was 5.60% with excess (5.37%) as the main performance. Abnormality in early pregnancy was the lowest (1.26%), which was similar with rate of lacking (0.76%) and excess (0.5%). With the increase of gestational age, the abnormal rate of vitamin E also increased gradually, and it reached the highest in late pregnancy (15.32%), which was all characterized by excessive vitamin E.Conclusion The serum levels of vitamin A, E are different during pregnancy period, vitamin A is presence of lack, while vitamin E is presence of excess. Therefore attaching great importance to the monitoring of vitamin A, E and other micronutrients level in pregnancy, guiding rational correct prenatal vitamins supplement have important significance to the safety of maternal and fetal.
