CAJ | 학술논문

目的研究胰腺黏液性囊性肿瘤(MCN)的临床特征.方法运用汇集分析的方法,以PubMed为检索数据库,对2014年5月31日之前发表的关于胰腺MCN文献中经病理学证实的临床病例进行提取分析,主要包括患者的性别、年龄、主要临床表现、主要相关伴随疾病、肿瘤的形态学类型、解剖学分布特征、病理学类型等.结果共汇集文献184篇,病例2 958例.胰腺MCN多发于中老年人群,女性发病率远高于男性;可发生于胰腺的各个部位,多位于胰腺体尾部;汇集的病例约3/4为良性;胰腺MCN的临床表现缺乏特异性,最常见症状为上腹部疼痛,其次为上腹部包块、体重减轻等症状,且有近1/3病例无明显症状.结论胰腺MCN缺乏特异性临床表现.在临床工作中应注意对胰腺MCN的诊断与鉴别,其治疗则需结合肿瘤的部位、局部特征及患者身体状况综合决定.
목적 연구이선점액성낭성종류(MCN)적림상특정.방법 운용회집분석적방법,이PubMed위검색수거고,대2014년5월31일지전발표적관우이선MCN문헌중경병이학증실적림상병례진행제취분석,주요포괄환자적성별、년령、주요림상표현、주요상관반수질병、종류적형태학류형、해부학분포특정、병이학류형등.결과 공회집문헌184편,병례2 958례.이선MCN다발우중노년인군,녀성발병솔원고우남성;가발생우이선적각개부위,다위우이선체미부;회집적병례약3/4위량성;이선MCN적림상표현결핍특이성,최상견증상위상복부동통,기차위상복부포괴、체중감경등증상,차유근1/3병례무명현증상.결론 이선MCN결핍특이성림상표현.재림상공작중응주의대이선MCN적진단여감별,기치료칙수결합종류적부위、국부특정급환자신체상황종합결정.
Objective To study the clinical features of pancreatic mucinous cystic neoplasm (MCN).Methods Clinical cases with a positive histopathologic diagnosis of pancreatic MCN published before May 31st, 2014 in the PubMed database were studied.Results There were 184 articles on 2958 of such cases.Pancreatic MCN was more prevalent in the middle-aged and elderly populations.The incidence was higher in female.Pancreatic MCN occurred in all parts of the pancreas, but the body and tail of the pancreas were the more usual locations.Benign neoplasm accounted for nearly 3/4 of all the cases.The clinical manifestations of pancreatic MCN lacked specificity.The most common presentation was epigastric pain, followed by epigastric mass and weight loss.Nearly 1/3 of cases had no obvious manifestation.Conclusions The clinical manifestations of pancreatic MCN lacked specificity.Awareness should be paid to its diagnosis.Tumor location, local characteristics and physical condition of the patient determine the therapy of this tumor.