CAJ | 학술논문

目的：研究小型猪根尖孔径大小对小型猪实验性牙髓炎组织病理进展的影响,为建立小型猪牙髓炎动物模型选择合适的实验牙。方法选用18~20月龄的小型猪,体视显微镜下应用Digimizer软件测量小型猪的各组牙齿根尖孔径的大小。使用龈上菌斑诱导法,建立小型猪前牙和前磨牙牙髓炎模型,通过组织病理学观察,分析不同根尖孔径牙髓炎症的特点。结果18~20月龄小型猪后牙根尖孔径与人牙根尖孔径较为接近；根尖孔较大牙齿的牙髓炎症情况明显轻于根尖孔较小的牙齿。结论根尖孔径大小对牙髓炎进展有影响,18~20月龄第二、三前磨牙可作为建立小型猪牙髓炎模型较为理想的实验牙。
목적：연구소형저근첨공경대소대소형저실험성아수염조직병리진전적영향,위건립소형저아수염동물모형선택합괄적실험아。방법선용18~20월령적소형저,체시현미경하응용Digimizer연건측량소형저적각조아치근첨공경적대소。사용간상균반유도법,건립소형저전아화전마아아수염모형,통과조직병이학관찰,분석불동근첨공경아수염증적특점。결과18~20월령소형저후아근첨공경여인아근첨공경교위접근；근첨공교대아치적아수염증정황명현경우근첨공교소적아치。결론근첨공경대소대아수염진전유영향,18~20월령제이、삼전마아가작위건립소형저아수염모형교위이상적실험아。
Objective To examine the effect of apical size on experimentally induced pulpitis, and to determine the optimal teeth for establishing experimentally induced pulpitis in miniature swine. Methods Four 18-month-old miniature swine were used in this study. The apical sizes of incisors, canines, premolars and molars were measured using stereoscopy by Digimizer software, respectively. Meanwhile, experimentally induced pulpits models were established by supragingival plaque methods and the characteristics of inflammatory progress were analyzed by histology. Results In 18-20-month-old miniature swine, the premolars had a very comparable size to human permanent molars. Histological studies revealed that apical size had a significant effect on the pathological progress of induced pulpitis. Larger size of apical foramen tended to have localized pulpitis compared to smaller one. Conclusion Apical size has an impact on the pathological progress of pulpitis. In the 18-20-month old miniature swine, the second and third premolars are most suitable for establishing pulpitis models.