CAJ | 학술논문

髓系来源抑制细胞（ Myeloid－derived suppressor cells，MDSCs）是一群未成熟的髓系来源细胞，参与了肿瘤的增殖、侵润、肿瘤血管生成、免疫抑制等病理过程，促进肿瘤的发生和生长；反过来，肿瘤以及肿瘤微环境也可促使MDSCs进一步增殖。本文就MDSCs的产生以及和肿瘤之间的相互作用以及部分作用机制做一综述。
수계래원억제세포（ Myeloid－derived suppressor cells，MDSCs）시일군미성숙적수계래원세포，삼여료종류적증식、침윤、종류혈관생성、면역억제등병리과정，촉진종류적발생화생장；반과래，종류이급종류미배경야가촉사MDSCs진일보증식。본문취MDSCs적산생이급화종류지간적상호작용이급부분작용궤제주일종술。
A group of immature myeloid-derived cells called Myeloid-derived suppressor cells ( MDSCs) which involved in tumor proliferation, invasion and pathological processes, and promote tumorigenesis and growth;and the tumor microenvironment may also in-duce MDSCs further proliferation.This article will do a review about the MDSCs on the generation and interaction between tumor and part of the mechanism.