CAJ | 학술논문

目的：探讨消化系统神经内分泌肿瘤（GEP-NETs）临床病理特征及其转移的影响因素。方法：回顾性分析198例GEP-NETs患者与GEP-NETs病理学类型及其转移的关系。结果：不同病理学类型GEP-NETs患者性别、发病年龄、淋巴结转移等情况的差异均具有统计学意义。单因素分析结果显示，性别、年龄、腹痛、肿瘤数目、肿瘤部位与GEP-NETs转移无明显相关性，而大便性状的改变、黑便或大便带血、肿瘤直径、病理学分级与GEP-NETs转移相关。logistics多因素回归分析显示，肿瘤直径与病理学分级是GEP-NETs发生转移的独立危险因素。结论：性别、发病年龄、淋巴结转移是影响GEP-NETs病理学类型的重要影响因素，肿瘤直径与病理学分级与GEP-NETs转移紧密相关。
목적：탐토소화계통신경내분비종류（GEP-NETs）림상병리특정급기전이적영향인소。방법：회고성분석198례GEP-NETs환자여GEP-NETs병이학류형급기전이적관계。결과：불동병이학류형GEP-NETs환자성별、발병년령、림파결전이등정황적차이균구유통계학의의。단인소분석결과현시，성별、년령、복통、종류수목、종류부위여GEP-NETs전이무명현상관성，이대편성상적개변、흑편혹대편대혈、종류직경、병이학분급여GEP-NETs전이상관。logistics다인소회귀분석현시，종류직경여병이학분급시GEP-NETs발생전이적독립위험인소。결론：성별、발병년령、림파결전이시영향GEP-NETs병이학류형적중요영향인소，종류직경여병이학분급여GEP-NETs전이긴밀상관。
Objective:To discuss the clinical pathological features of gastroenteropancreatic neuroendocrine tumors (GEP-NETs) and the influence factors of its transformation.Methods: The clinical data of 198 cases of GEP-NETs patients as well as the relationship between the pathological types and the transformation of GEP-NETs were retrospectively analyzed. Results: The differences among the sex, the age at onset and the lymph node metastasis of GEP-NETs patients with different pathological types were statistically signiifcant. Single factor analysis showed that sex, age, abdominal pain, tumor number, tumor location had no signiifcant correlationwith GEP-NETs transformation, but the change of stool traits, black stool or bloody stool, tumor diameter and grading of pathology had signiifcant relation to GEP-NETs transformation. Logistics multivariate regression analysis showed that tumor diameter and grading of pathology were the independent risk factors of GEP-NETs transformation. Conclusion:Sex, age at onset and lymph node metastasis are important inlfuence factors of GEP-NETs pathological types. Tumor diameter and grading of pathology have signiifcant relation to GEP-NETs transformation.