中国医学前沿杂志(电子版)
中國醫學前沿雜誌(電子版)
중국의학전연잡지(전자판)
Chinese Journal of the Frontiers of Medical Science (Electronic Version)
2015年
9期
40-42
,共3页
妊娠%梅毒%治疗时机%新生儿%妊娠结局
妊娠%梅毒%治療時機%新生兒%妊娠結跼
임신%매독%치료시궤%신생인%임신결국
Pregnancy%Syphilis%Treatment opportunity%Neonate%Pregnant outcomes
目的:探究不同治疗时机对妊娠合并梅毒患者妊娠结局及胎儿预后的影响。方法选取2008年8月至2012年8月本院收治的66例妊娠合并梅毒患者为研究对象,按照不同治疗时机将患者分为A组(孕周<12周)、B组(孕周13~28周)、C组(孕周>29周),比较三组患者妊娠结局、先天梅毒患儿发生率及母婴RPR滴度。结果三组患者足月分娩率、早产率比较差异具有显著性(P<0.05),而三组低体重儿、流产、死胎的发生率比较差异均无显著性(P>0.05)。A组中均为正常新生儿,B组和C组先天梅毒患儿发生率分别为2.85%和20.00%,显著高于A组(P<0.05)。A组中RPR滴度<1︰8者比例最高,C组最低,组间比较差异具有显著性(P<0.05)。结论早期诊断及科学规范的抗梅毒治疗能够明显改善梅毒患者妊娠结局,降低新生儿早产率以及先天梅毒患儿的发生率,对新生儿预后意义重大,安全性高。
目的:探究不同治療時機對妊娠閤併梅毒患者妊娠結跼及胎兒預後的影響。方法選取2008年8月至2012年8月本院收治的66例妊娠閤併梅毒患者為研究對象,按照不同治療時機將患者分為A組(孕週<12週)、B組(孕週13~28週)、C組(孕週>29週),比較三組患者妊娠結跼、先天梅毒患兒髮生率及母嬰RPR滴度。結果三組患者足月分娩率、早產率比較差異具有顯著性(P<0.05),而三組低體重兒、流產、死胎的髮生率比較差異均無顯著性(P>0.05)。A組中均為正常新生兒,B組和C組先天梅毒患兒髮生率分彆為2.85%和20.00%,顯著高于A組(P<0.05)。A組中RPR滴度<1︰8者比例最高,C組最低,組間比較差異具有顯著性(P<0.05)。結論早期診斷及科學規範的抗梅毒治療能夠明顯改善梅毒患者妊娠結跼,降低新生兒早產率以及先天梅毒患兒的髮生率,對新生兒預後意義重大,安全性高。
목적:탐구불동치료시궤대임신합병매독환자임신결국급태인예후적영향。방법선취2008년8월지2012년8월본원수치적66례임신합병매독환자위연구대상,안조불동치료시궤장환자분위A조(잉주<12주)、B조(잉주13~28주)、C조(잉주>29주),비교삼조환자임신결국、선천매독환인발생솔급모영RPR적도。결과삼조환자족월분면솔、조산솔비교차이구유현저성(P<0.05),이삼조저체중인、유산、사태적발생솔비교차이균무현저성(P>0.05)。A조중균위정상신생인,B조화C조선천매독환인발생솔분별위2.85%화20.00%,현저고우A조(P<0.05)。A조중RPR적도<1︰8자비례최고,C조최저,조간비교차이구유현저성(P<0.05)。결론조기진단급과학규범적항매독치료능구명현개선매독환자임신결국,강저신생인조산솔이급선천매독환인적발생솔,대신생인예후의의중대,안전성고。
ObjectiveTo study the effect of different treatment opportunities on the pregnancy outcome and fetal prognosis of pregnant women with syphilis.Method66 cases of pregnant women with syphilis were selected from August 2008 to August 2012 in our hospital for the study, according to the different treatment opportunities, they were divided into group A (gestational weeks<12 weeks), group B (13 weeks<gestational weeks<28 weeks), group C (gestational weeks> 29 weeks), compared three groups patients with pregnant outcomes, incidence of neonatal congenital syphilis, maternal RPR titer.ResultAfter treatment, term delivery rate and premature delivery rate of three groups were signiifcant difference (P<0.05), whereas the incidence of low birth weight infant, abortus, fetal death of three groups had no signiifcant difference (P>0.05). Group A were all normal neonate, congenital syphilis incidence of group B and group C was 2.85% and 20.00% respectively, signiifcantly higher than group A (P<0.05). Group A RPR titer<1︰8 was highest among three groups, group C was the lowest, the difference between the three groups was signiifcant (P<0.05). ConclusionEarly treatment for women with syphilis can improve pregnancy outcomes and fetal outcomes, which can effectively reduce syphilis infection rate and it is safe.