中国医学前沿杂志（电子版）
中國醫學前沿雜誌（電子版）
중국의학전연잡지（전자판）
Chinese Journal of the Frontiers of Medical Science (Electronic Version)
2015年
9期
26-28
,共3页
彭华%邱俊%易勇%丁常云
彭華%邱俊%易勇%丁常雲
팽화%구준%역용%정상운
急性颅脑损伤%血糖%胰岛素%胰高血糖素
急性顱腦損傷%血糖%胰島素%胰高血糖素
급성로뇌손상%혈당%이도소%이고혈당소
Acute craniocerebral injury%Blood glucose%Insulin%Glucagon
目的：探讨急性颅脑损伤患者血糖、胰岛素、胰高血糖素水平的变化情况及临床意义。方法将2011年1月至2014年6月本院收治的急性颅脑损伤患者138例纳入研究组，根据格拉斯哥昏迷评分（GCS）将其分为重型颅脑损伤（GCS评分3～8分）65例，中型颅脑损伤（GCS评分9～12分）55例，轻型颅脑损伤（GCS评分13～15分）18例。另选同期本院120例健康体检者纳入对照组。比较并分析不同程度和不同预后颅脑损伤患者的血糖、胰岛素及胰高血糖素水平。结果重型和中型颅脑损伤患者血糖、胰岛素及胰高血糖素水平均明显高于对照组（P＜0.05），而轻型颅脑损伤患者血糖、胰岛素及胰高血糖素水平有所提高，但与对照组比较无显著差异（P＞0.05）。重度残疾和死亡及植物状态生存患者血糖、胰岛素及胰高血糖素水平均明显高于预后良好患者（P＜0.05），而轻度残疾患者血糖、胰岛素及胰高血糖素水平有所提高，但与预后良好患者比较无显著差异（P＞0.05）。结论有效控制急性颅脑损伤患者的血糖水平，可以减少患者继发性脑损伤，改善预后。
目的：探討急性顱腦損傷患者血糖、胰島素、胰高血糖素水平的變化情況及臨床意義。方法將2011年1月至2014年6月本院收治的急性顱腦損傷患者138例納入研究組，根據格拉斯哥昏迷評分（GCS）將其分為重型顱腦損傷（GCS評分3～8分）65例，中型顱腦損傷（GCS評分9～12分）55例，輕型顱腦損傷（GCS評分13～15分）18例。另選同期本院120例健康體檢者納入對照組。比較併分析不同程度和不同預後顱腦損傷患者的血糖、胰島素及胰高血糖素水平。結果重型和中型顱腦損傷患者血糖、胰島素及胰高血糖素水平均明顯高于對照組（P＜0.05），而輕型顱腦損傷患者血糖、胰島素及胰高血糖素水平有所提高，但與對照組比較無顯著差異（P＞0.05）。重度殘疾和死亡及植物狀態生存患者血糖、胰島素及胰高血糖素水平均明顯高于預後良好患者（P＜0.05），而輕度殘疾患者血糖、胰島素及胰高血糖素水平有所提高，但與預後良好患者比較無顯著差異（P＞0.05）。結論有效控製急性顱腦損傷患者的血糖水平，可以減少患者繼髮性腦損傷，改善預後。
목적：탐토급성로뇌손상환자혈당、이도소、이고혈당소수평적변화정황급림상의의。방법장2011년1월지2014년6월본원수치적급성로뇌손상환자138례납입연구조，근거격랍사가혼미평분（GCS）장기분위중형로뇌손상（GCS평분3～8분）65례，중형로뇌손상（GCS평분9～12분）55례，경형로뇌손상（GCS평분13～15분）18례。령선동기본원120례건강체검자납입대조조。비교병분석불동정도화불동예후로뇌손상환자적혈당、이도소급이고혈당소수평。결과중형화중형로뇌손상환자혈당、이도소급이고혈당소수평균명현고우대조조（P＜0.05），이경형로뇌손상환자혈당、이도소급이고혈당소수평유소제고，단여대조조비교무현저차이（P＞0.05）。중도잔질화사망급식물상태생존환자혈당、이도소급이고혈당소수평균명현고우예후량호환자（P＜0.05），이경도잔질환자혈당、이도소급이고혈당소수평유소제고，단여예후량호환자비교무현저차이（P＞0.05）。결론유효공제급성로뇌손상환자적혈당수평，가이감소환자계발성뇌손상，개선예후。
ObjectiveTo investigate the changes of blood glucose, insulin and glucagon in patients with acute craniocerebral injury and its clinical signiifcance.MethodFrom January 2011 to June 2014, 138 patients with acute craniocerebral injury were included in study group in our hospital. According to GCS, patients in study group were divided into severe craniocerebral injury (GCS score was 3~8 points) with 65 cases, moderate craniocerebral injury (GCS score was 9~12 points) with 55 cases, mild craniocerebral injury (GCS score was 13~15 points) with 18 cases. During the same period, 120 cases of health physical examination resrarch objects were selected as control group. The levels of blood glucose, insulin, glucagon of patients in different degrees and prognosis were compared and analyzed.ResultThe levels of blood glucose, insulin, glucagon of patients with severe craniocerebral injury and moderate craniocerebral injury were signiifcantly higher than control group (P<0.05). While the levels of blood glucose, insulin, glucagon of patients with mild craniocerebral injury were increased, but the differences were not significant statistically compared with control group (P>0.05). The levels of blood glucose, insulin, glucagon of patients with severe disability, death and vegetative state survival were increased signiifcantly compared with patients with well prognosis (P<0.05). While the levels of blood glucose, insulin, glucagon of patients with mild disability were increased, but the differences were not signiifcant statistically compared with patients with well prognosis (P>0.05).ConclusionEffectively control of blood glucose level in patients with acute craniocerebral injury can reduce the secondary brain injury, improve prognosis.
