中国继续医学教育
中國繼續醫學教育
중국계속의학교육
China Continuing Medical Education
2015年
29期
43-44
,共2页
超敏C反应蛋白%冠心病
超敏C反應蛋白%冠心病
초민C반응단백%관심병
HS-CRP%Coronary heart disease
目的：探讨超敏C反应蛋白（HS-CRP）检测在冠心病（CHD）诊断中的应用价值。方法结合临床检查及冠脉造影情况，将180例冠心病患者分为稳定性心绞痛（SAP）、不稳定性心绞痛（UAP）、急性心肌梗死（AMI）3个组，分别测定180例冠心病患者血清超敏 C 反应蛋白（HS-CRP）、肌酸激酶（CK）、肌酸激酶同工酶（CK-MB），并与80例健康人做对比。结果与正常对照组比较，CHD组血清HS-CRP均升高，P＜0.05，差异具有统计学意义，且AMI组血清的HS-CRP浓度高于UAP组，P＜0.05，差异具有统计学意义，UAP组血清的Hs-CRP浓度高于SAP组，P＜0.05，差异具有统计学意义，且AMI组治疗后HS-CRP浓度下降，冠心病阳性检出率HS-CRP（90.0%）＞CK（35.6%）＞CK-MB（38.3%）。结论血清HS -CRP水平高低与CHD病情密切相关，可作为冠心病患者病情严重程度的敏感性指标。
目的：探討超敏C反應蛋白（HS-CRP）檢測在冠心病（CHD）診斷中的應用價值。方法結閤臨床檢查及冠脈造影情況，將180例冠心病患者分為穩定性心絞痛（SAP）、不穩定性心絞痛（UAP）、急性心肌梗死（AMI）3箇組，分彆測定180例冠心病患者血清超敏 C 反應蛋白（HS-CRP）、肌痠激酶（CK）、肌痠激酶同工酶（CK-MB），併與80例健康人做對比。結果與正常對照組比較，CHD組血清HS-CRP均升高，P＜0.05，差異具有統計學意義，且AMI組血清的HS-CRP濃度高于UAP組，P＜0.05，差異具有統計學意義，UAP組血清的Hs-CRP濃度高于SAP組，P＜0.05，差異具有統計學意義，且AMI組治療後HS-CRP濃度下降，冠心病暘性檢齣率HS-CRP（90.0%）＞CK（35.6%）＞CK-MB（38.3%）。結論血清HS -CRP水平高低與CHD病情密切相關，可作為冠心病患者病情嚴重程度的敏感性指標。
목적：탐토초민C반응단백（HS-CRP）검측재관심병（CHD）진단중적응용개치。방법결합림상검사급관맥조영정황，장180례관심병환자분위은정성심교통（SAP）、불은정성심교통（UAP）、급성심기경사（AMI）3개조，분별측정180례관심병환자혈청초민 C 반응단백（HS-CRP）、기산격매（CK）、기산격매동공매（CK-MB），병여80례건강인주대비。결과여정상대조조비교，CHD조혈청HS-CRP균승고，P＜0.05，차이구유통계학의의，차AMI조혈청적HS-CRP농도고우UAP조，P＜0.05，차이구유통계학의의，UAP조혈청적Hs-CRP농도고우SAP조，P＜0.05，차이구유통계학의의，차AMI조치료후HS-CRP농도하강，관심병양성검출솔HS-CRP（90.0%）＞CK（35.6%）＞CK-MB（38.3%）。결론혈청HS -CRP수평고저여CHD병정밀절상관，가작위관심병환자병정엄중정도적민감성지표。
Objective To explore the clinical diagnostic value of the determination of serum HS-CRP.Methods Combined with clinical examination and coronary angiography,180 cases of coronary heart disease were divided into three groups,including stable angina pectoris group, unstable angina pectoris group and acute myocardial infarction group, HS-CRP, CK and CK-MB were parallelly detected and performed the comparative analysis in 180 cases of observation group and 80 cases of healthy control group.Results Compared with the healthy control group,the serum HS-CRP in CHD groups was significantly increased,P<0.05, had difference statistically significance, the serum HS-CRP in AMI group was higher than that in UAP group,P<0.05, had difference statistically significance, the serum HS-CRP in UAP group was significantly higher than that of group SAP,P<0.05, had difference statistically significance, the serum HS-CRP in the AMI group after treatment has decreased significantly,the positive rate in CHD groups was HS-CRP (90.0%)>CK(35.6%)>CK-MB(38.3%).Conclusion It is suggested that the serum HS-CRP level is closely correlated with severity degree of the coronary heart disease,may be used as sensitive indexes of the severity of illness in patients with coronary heart disease.
